ID   WCAL_SALTY              Reviewed;         406 AA.
AC   P26388;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Putative colanic acid biosynthesis glycosyltransferase WcaL;
DE            EC=2.4.-.-;
GN   Name=wcaL; OrderedLocusNames=STM2100;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1710759; DOI=10.1111/j.1365-2958.1991.tb00741.x;
RA   Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
RT   "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella
RT   serovar typhimurium (strain LT2).";
RL   Mol. Microbiol. 5:695-713(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- PATHWAY: Slime biogenesis; slime polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; X56793; CAA40132.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL21004.1; -; Genomic_DNA.
DR   PIR; S15296; S15296.
DR   RefSeq; NP_461045.1; NC_003197.2.
DR   RefSeq; WP_000868521.1; NC_003197.2.
DR   AlphaFoldDB; P26388; -.
DR   SMR; P26388; -.
DR   STRING; 99287.STM2100; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   PaxDb; P26388; -.
DR   DNASU; 1253621; -.
DR   EnsemblBacteria; AAL21004; AAL21004; STM2100.
DR   GeneID; 1253621; -.
DR   KEGG; stm:STM2100; -.
DR   PATRIC; fig|99287.12.peg.2222; -.
DR   HOGENOM; CLU_009583_14_3_6; -.
DR   OMA; RIALRGW; -.
DR   PhylomeDB; P26388; -.
DR   BioCyc; SENT99287:STM2100-MON; -.
DR   UniPathway; UPA00936; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0045228; P:slime layer polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR023884; Colanic_acid_synth_WcaL.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   Pfam; PF13439; Glyco_transf_4; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR04005; wcaL; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW   Transferase.
FT   CHAIN           1..406
FT                   /note="Putative colanic acid biosynthesis
FT                   glycosyltransferase WcaL"
FT                   /id="PRO_0000080312"
SQ   SEQUENCE   406 AA;  45193 MW;  FFAA8FA956FD309F CRC64;
     MKVSFFLLKF PLSSETFVLN QITAFIDMGH EVEIVALQKG DTQHTHAAWE KYGLAAKTRW
     LQDEPQGRLA KLRYRACKTL PGLHRAATWK ALNFTRYGDE SRNLILSAIC AQVSQPFVAD
     VFIAHFGPAG VTAAKLRELG VLRGKIATIF HGIDISSREV LSHYTPEYQQ LFRRGDLMLP
     ISDLWAGRLK SMGCPPEKIA VSRMGVDMTR FTHRSVKAPG MPLEMISVAR LTEKKGLHVA
     IEACRQLKAQ GVAFRYRILG IGPWERRLRT LIEQYQLEDV IEMPGFKPSH EVKAMLDDAD
     VFLLPSITGT DGDMEGIPVA LMEAMAVGIP VVSTVHSGIP ELVEAGKSGW LVPENDAQAL
     AARLAEFSRI DHDTLESVIT RAREKVAQDF NQQAINRQLA SLLQTI