ID   WCAM_SALTY              Reviewed;         467 AA.
AC   P26389;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Colanic acid biosynthesis protein WcaM;
GN   Name=wcaM; OrderedLocusNames=STM2099;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1710759; DOI=10.1111/j.1365-2958.1991.tb00741.x;
RA   Jiang X.-M., Neal B., Santiago F., Lee S.J., Romana L.K., Reeves P.R.;
RT   "Structure and sequence of the rfb (O antigen) gene cluster of Salmonella
RT   serovar typhimurium (strain LT2).";
RL   Mol. Microbiol. 5:695-713(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- PATHWAY: Slime biogenesis; slime polysaccharide biosynthesis.
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DR   EMBL; X56793; CAA40113.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL21003.1; -; Genomic_DNA.
DR   PIR; S15297; S15297.
DR   RefSeq; NP_461044.1; NC_003197.2.
DR   RefSeq; WP_001111841.1; NC_003197.2.
DR   AlphaFoldDB; P26389; -.
DR   SMR; P26389; -.
DR   STRING; 99287.STM2099; -.
DR   PaxDb; P26389; -.
DR   EnsemblBacteria; AAL21003; AAL21003; STM2099.
DR   GeneID; 1253620; -.
DR   KEGG; stm:STM2099; -.
DR   PATRIC; fig|99287.12.peg.2221; -.
DR   HOGENOM; CLU_046699_0_0_6; -.
DR   OMA; YDNDYPE; -.
DR   PhylomeDB; P26389; -.
DR   BioCyc; SENT99287:STM2099-MON; -.
DR   UniPathway; UPA00936; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0045228; P:slime layer polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.160.20.10; -; 1.
DR   InterPro; IPR023882; Colanic_acid_synth_WcaM.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   InterPro; IPR006311; TAT_signal.
DR   SUPFAM; SSF51126; SSF51126; 1.
DR   TIGRFAMs; TIGR04004; WcaM; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Lipopolysaccharide biosynthesis; Reference proteome.
FT   CHAIN           1..467
FT                   /note="Colanic acid biosynthesis protein WcaM"
FT                   /id="PRO_0000065959"
SQ   SEQUENCE   467 AA;  50958 MW;  9DCCFD551218E6E8 CRC64;
     MPATKFSRRT LLTAGSALAV LPFLRALPVQ AREPRETVDI KDYPADDGIA SFKQAFADGQ
     TVVVPPGWVC ENINAAITIP AGKTLRVQGA VRGNGRGRFI LQDGCQVVGE QGGSLHNVTL
     DVRGSDCVIK GVAMSGFGPV AQIFIGGKEP QVMRNLIIDD ITVTHANYAI LRQGFHNQMD
     GARITHSRFS DLQGDAIEWN VAIHDRDILI SDHVIERINC TNGKINWGIG IGLAGSTYDN
     SYPEDQAVKN FVVANITGSD CRQLVHVENG KHFVIRNVKA KNITPGFSKN AGIDNATIAI
     YGCDNFVIDN IDMTNSAGML IGYGVVKGKY LSIPQNFKLN AIRLDNRQVA YKLRGIQISS
     GNTPSFVAIT NVRMTRATLE LHNQPQHLFL RNINVMQTSA IGPALKMHFD LRKDVRGQFM
     ARQDTLLSLA NVHAINENGQ SSVDIDRINH QTVNVEAVNF SLPKRGG