WDCP_DANRE
ID WDCP_DANRE Reviewed; 714 AA.
AC Q5RFV8; Q5BKX4;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 2.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=WD repeat and coiled-coil-containing protein;
GN Name=wdcp; ORFNames=si:dkeyp-115a10.2, zgc:103511;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH90896.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAI21305.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CR545466; CAI21305.1; ALT_INIT; Genomic_DNA.
DR EMBL; BC090896; AAH90896.1; ALT_INIT; mRNA.
DR RefSeq; NP_001013552.1; NM_001013534.1.
DR AlphaFoldDB; Q5RFV8; -.
DR STRING; 7955.ENSDARP00000011821; -.
DR PaxDb; Q5RFV8; -.
DR PRIDE; Q5RFV8; -.
DR GeneID; 541407; -.
DR KEGG; dre:541407; -.
DR CTD; 80304; -.
DR ZFIN; ZDB-GENE-050320-107; wdcp.
DR eggNOG; ENOG502QUUX; Eukaryota.
DR InParanoid; Q5RFV8; -.
DR OrthoDB; 435947at2759; -.
DR PhylomeDB; Q5RFV8; -.
DR TreeFam; TF333528; -.
DR PRO; PR:Q5RFV8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0019900; F:kinase binding; IBA:GO_Central.
DR InterPro; IPR028041; WDCP.
DR PANTHER; PTHR14897; PTHR14897; 1.
DR Pfam; PF15390; WDCP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..714
FT /note="WD repeat and coiled-coil-containing protein"
FT /id="PRO_0000299504"
FT REPEAT 55..98
FT /note="WD 1"
FT REPEAT 154..194
FT /note="WD 2"
FT REGION 432..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 567..595
FT /evidence="ECO:0000255"
FT CONFLICT 23
FT /note="V -> A (in Ref. 2; AAH90896)"
FT /evidence="ECO:0000305"
FT CONFLICT 452
FT /note="E -> G (in Ref. 2; AAH90896)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 714 AA; 79171 MW; E4BA9AF14E1A1764 CRC64;
MELGKAKLLR TGLNTLHQAI HPVHGIAWTD GKQVCLTSLF SVEGEPKFGD TNVIGQFEHV
LGLFWGPLCC SGSPALLAVQ HKKHVTVWQL QLSALEQNKL LCTQTCEMSE PFPLLSQGCV
WHPKMDVLAI LTKRDASVLF SVRVDNRRVK ADIKGSGLIH CACWTKDGTR LVVAIGSALH
SYTWNDIQKS LVPCSFCPIF DVGGYICAIE STDEAQVAVA TELPLDKICG LNAGMAFDLP
NESEGLCRPS AALTVDTDYY LDRRRSCDSE RSGHASSGPI DLTNLLAKHR KSDPSPLIHL
RKRDNLTGTG QDSSHLILVT YERKVTTTRK VSIPGILVPD IIAFDPNGHT VAVASNTCNM
ILVYCITDSS MPNVQQIQLQ KNERPKGVCF FTNKMLLFMI GRQKSNDPAF LPSSNTDKYI
LRLTAKELVF DEESTTKSES PSQHHGIRRH SENFTKEDRL SIKDLILPGG SVIVSPSSRR
KLIEEVRSSD LSPVASSADF SDRASSASSV TLENYDMDHI TRMASLAVAG QASRDSSRPC
SPRYETSEKL YSDATPPKNS KEKNLEQLTQ NMERIFTRFA EVQQCLSEIR EFTQNGKKIA
CSYPSAYEPQ YVHITCQKQL SENVYTDERR PLLLCGGRIC LRVVQELFGL TVVEMMHGPM
WITLVADADG FVPLTFKHKD ELTIRSARRK SPARPPSGAD DFPPESPKSP SMEK
