WDR12_ORYSJ
ID WDR12_ORYSJ Reviewed; 436 AA.
AC Q8H594;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=Ribosome biogenesis protein WDR12 homolog {ECO:0000255|HAMAP-Rule:MF_03029};
GN Name=WDR12 {ECO:0000305};
GN OrderedLocusNames=Os07g0600400 {ECO:0000312|EMBL:BAT02519.1},
GN LOC_Os07g40930 {ECO:0000305};
GN ORFNames=OJ1634_B10.122 {ECO:0000312|EMBL:BAC15510.1},
GN OsJ_25010 {ECO:0000312|EMBL:EEE67534.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000312|EMBL:BAC15510.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_03029}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC Rule:MF_03029}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03029}.
CC -!- SIMILARITY: Belongs to the WD repeat WDR12/YTM1 family.
CC {ECO:0000255|HAMAP-Rule:MF_03029}.
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DR EMBL; AP003840; BAC15510.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF22111.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT02519.1; -; Genomic_DNA.
DR EMBL; CM000144; EEE67534.1; -; Genomic_DNA.
DR RefSeq; XP_015647915.1; XM_015792429.1.
DR AlphaFoldDB; Q8H594; -.
DR SMR; Q8H594; -.
DR STRING; 4530.OS07T0600400-01; -.
DR PaxDb; Q8H594; -.
DR PRIDE; Q8H594; -.
DR EnsemblPlants; Os07t0600400-01; Os07t0600400-01; Os07g0600400.
DR GeneID; 4343819; -.
DR Gramene; Os07t0600400-01; Os07t0600400-01; Os07g0600400.
DR KEGG; osa:4343819; -.
DR eggNOG; KOG0313; Eukaryota.
DR HOGENOM; CLU_000288_57_0_1; -.
DR InParanoid; Q8H594; -.
DR OMA; VDCTRTK; -.
DR OrthoDB; 1540178at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000007752; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03029; WDR12; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR012972; NLE.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR028599; WDR12/Ytm1.
DR Pfam; PF08154; NLE; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing;
KW WD repeat.
FT CHAIN 1..436
FT /note="Ribosome biogenesis protein WDR12 homolog"
FT /id="PRO_0000437497"
FT REPEAT 109..147
FT /note="WD 1"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 149..193
FT /note="WD 2"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 203..242
FT /note="WD 3"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 273..311
FT /note="WD 4"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 313..353
FT /note="WD 5"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 359..399
FT /note="WD 6"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REPEAT 402..436
FT /note="WD 7"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REGION 13..97
FT /note="Ubiquitin-like (UBL) domain"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03029"
FT REGION 240..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 436 AA; 47660 MW; 6A9DC6C6A92162DF CRC64;
MDSGGASDPS RQVRVRFLTK LPAPLRAPPT SIAVPADLTR MGLSEIVNSL LLAASPDHQA
QPFDFLVDGE LVRLPLQEFL LAKGISVERV LELEYVKAVA PRKQEDPCPH DDWVSAVDGS
NPSFVLTGCY DGLARIWRDA SECTHILEGH SDGITSARFI NKGETEDRLH VVTASKDRSL
RLFKFDTSVS VPKQIGAYKI LRGHTSSVQS VAVDPSTNMI CSGSWDNSIK LWSVEGSEED
GDTVSVKKRR TNSDSSGPEE SLFEGSATST FLGHTQCVSA VTWPERQTIY SASWDHSVRQ
WDVQTGKETW NMVSGKALNC LDCGGESSSL IAAGGSDPVL RVWDPRKPGT LAPIFQFSSH
KSWISACKWH PSSWFHLVSS SFDGKVMLWD LRTAWPLASV ESHKDKVLCA DWWKGDSVIS
GGADSKLCIA SGIEIV
