ID   WDR37_XENLA             Reviewed;         495 AA.
AC   Q6DDF0;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=WD repeat-containing protein 37;
GN   Name=wdr37;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2I8}. Nucleus
CC       {ECO:0000250|UniProtKB:Q9Y2I8}.
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DR   EMBL; BC077620; AAH77620.1; -; mRNA.
DR   RefSeq; NP_001086895.1; NM_001093426.1.
DR   AlphaFoldDB; Q6DDF0; -.
DR   SMR; Q6DDF0; -.
DR   BioGRID; 103590; 1.
DR   IntAct; Q6DDF0; 1.
DR   DNASU; 446730; -.
DR   GeneID; 446730; -.
DR   KEGG; xla:446730; -.
DR   CTD; 446730; -.
DR   Xenbase; XB-GENE-5740183; wdr37.L.
DR   OrthoDB; 1338925at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 446730; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..495
FT                   /note="WD repeat-containing protein 37"
FT                   /id="PRO_0000345131"
FT   REPEAT          154..194
FT                   /note="WD 1"
FT   REPEAT          197..236
FT                   /note="WD 2"
FT   REPEAT          280..319
FT                   /note="WD 3"
FT   REPEAT          322..361
FT                   /note="WD 4"
FT   REPEAT          366..404
FT                   /note="WD 5"
FT   REPEAT          407..446
FT                   /note="WD 6"
FT   REPEAT          453..494
FT                   /note="WD 7"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          237..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   495 AA;  54994 MW;  D0542D5C5B843F1B CRC64;
     MPTESGSWAA ARQTKQKRKS HSLSIKRTNS SEQDRLGLQR DMLEGQDSKL PPSVRNTLLE
     LFGQIEREFE NLYLENLELR REIDTLNDRL AVEGQAIDGA ELSKGQMKTK ASHSTSQLSQ
     KLKTTYKAST SKIVSSFKTT TSRAICQLVK DYVGHRDGLW DVSVTRTQPV VLGTASADHT
     ALLWSIETGK CLIKYVGHAG SVNSIKFHPT EQIALTASGD QTAHIWRYMV QLPTPQPMAD
     TSQISGEEEV DFSDKDENDG DGDASSDCPT VRVPLTALKS HQGVVIAADW LVGGKQAVTA
     SWDRTANLYD VETSELVHSL TGHDQELTHC CTHPTQRLVV TSSRDTTFRL WDFRDPSIHS
     VNVFQGHTDT VTSAVFTVGD NVVSGSDDRT VKVWDLKNMR SPIATIRTDS AVNRISVSVG
     QRIIALPHDN RQVRLFDISG VRLARLPRSN RQGHRRMVCC CAWSEDHPTC NLFSCGFDRQ
     AIGWNINIPA LLQEK