ID   WDR37_XENTR             Reviewed;         494 AA.
AC   A4IIX9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=WD repeat-containing protein 37;
GN   Name=wdr37;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2I8}. Nucleus
CC       {ECO:0000250|UniProtKB:Q9Y2I8}.
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DR   EMBL; BC136196; AAI36197.1; -; mRNA.
DR   RefSeq; NP_001096465.1; NM_001102995.1.
DR   AlphaFoldDB; A4IIX9; -.
DR   SMR; A4IIX9; -.
DR   PaxDb; A4IIX9; -.
DR   DNASU; 100125083; -.
DR   GeneID; 100125083; -.
DR   KEGG; xtr:100125083; -.
DR   CTD; 22884; -.
DR   Xenbase; XB-GENE-5740160; wdr37.
DR   eggNOG; KOG0300; Eukaryota.
DR   HOGENOM; CLU_036428_0_0_1; -.
DR   InParanoid; A4IIX9; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..494
FT                   /note="WD repeat-containing protein 37"
FT                   /id="PRO_0000345132"
FT   REPEAT          154..194
FT                   /note="WD 1"
FT   REPEAT          197..236
FT                   /note="WD 2"
FT   REPEAT          279..318
FT                   /note="WD 3"
FT   REPEAT          321..360
FT                   /note="WD 4"
FT   REPEAT          365..403
FT                   /note="WD 5"
FT   REPEAT          406..445
FT                   /note="WD 6"
FT   REPEAT          452..493
FT                   /note="WD 7"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          236..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   494 AA;  54870 MW;  69E2FFEFFBEE4907 CRC64;
     MPTESGSWAA ARQTKQKRKS HSLSIKRTNS SEQDRPGLQR EMLEGQDSKL PSSVRNTLLE
     LFGQIEREFE NLYLENLELR REIDTLNDRL AVEGQAIDGA ELSKGQMKTK ASHSTSQLSQ
     KLKTTYKAST SKIVSSFKTT TSRAICQLVK DYVGHRDGLW DVSVTRTQPV VLGTASADHT
     ALLWSIETGK CLIKYVGHAG SVNSIKFHPT EQIALTASGD QTAHIWRYMV QLPTPQPTAD
     TSISGEEEVD FSDKDENDGD GDASSDCPTV RVPLTALKSH QGVVIAADWL VGGKQAVTAS
     WDRTANLYDV ETSELVHSLT GHDQELTHCC THPTQRLVVT SSRDTTFRLW DFRDPSIHSV
     NVFQGHTDTV TSAVFTVGDN VVSGSDDRTV KVWDLKNMRS PIATIRTDSA INRISVSVGQ
     RIIALPHDNR QVRLFDMSGV RLARLPRSNR QGHRRMVCCC AWSEDHPTCN LFTCGFDRQA
     IGWNINIPAL LQEK