WDR38_MOUSE
ID WDR38_MOUSE Reviewed; 303 AA.
AC Q9D994;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=WD repeat-containing protein 38;
GN Name=Wdr38;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK007246; BAB24913.1; -; mRNA.
DR EMBL; AK077027; BAC36575.1; -; mRNA.
DR EMBL; AL844588; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC115629; AAI15630.1; -; mRNA.
DR CCDS; CCDS38119.1; -.
DR RefSeq; NP_083963.1; NM_029687.3.
DR AlphaFoldDB; Q9D994; -.
DR SMR; Q9D994; -.
DR STRING; 10090.ENSMUSP00000108493; -.
DR iPTMnet; Q9D994; -.
DR PhosphoSitePlus; Q9D994; -.
DR PaxDb; Q9D994; -.
DR PRIDE; Q9D994; -.
DR Antibodypedia; 64851; 22 antibodies from 12 providers.
DR DNASU; 76646; -.
DR Ensembl; ENSMUST00000039535; ENSMUSP00000043834; ENSMUSG00000035295.
DR Ensembl; ENSMUST00000112872; ENSMUSP00000108493; ENSMUSG00000035295.
DR GeneID; 76646; -.
DR KEGG; mmu:76646; -.
DR UCSC; uc008jnx.2; mouse.
DR CTD; 401551; -.
DR MGI; MGI:1923896; Wdr38.
DR VEuPathDB; HostDB:ENSMUSG00000035295; -.
DR eggNOG; KOG0263; Eukaryota.
DR eggNOG; KOG0266; Eukaryota.
DR GeneTree; ENSGT00940000162358; -.
DR HOGENOM; CLU_000288_57_33_1; -.
DR InParanoid; Q9D994; -.
DR OMA; RAKCLQV; -.
DR OrthoDB; 872177at2759; -.
DR PhylomeDB; Q9D994; -.
DR TreeFam; TF328741; -.
DR BioGRID-ORCS; 76646; 3 hits in 71 CRISPR screens.
DR PRO; PR:Q9D994; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q9D994; protein.
DR Bgee; ENSMUSG00000035295; Expressed in spermatid and 143 other tissues.
DR Genevisible; Q9D994; MM.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IMP:MGI.
DR Gene3D; 2.130.10.10; -; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..303
FT /note="WD repeat-containing protein 38"
FT /id="PRO_0000294441"
FT REPEAT 24..63
FT /note="WD 1"
FT REPEAT 66..105
FT /note="WD 2"
FT REPEAT 108..147
FT /note="WD 3"
FT REPEAT 150..189
FT /note="WD 4"
FT REPEAT 195..233
FT /note="WD 5"
FT REPEAT 236..277
FT /note="WD 6"
FT REPEAT 279..303
FT /note="WD 7"
SQ SEQUENCE 303 AA; 33052 MW; 321228D416559721 CRC64;
MEWAPMNIRA PTRLAVGRVR FYGQHHGEVN CSAFSPDGRT LLTASDDGCV YVWGTKSGRL
LWRLAGHRGP VKSCCFSPDG RLIASSSSDH SIRLWDVARS KCLHVLKGHQ RSVETVSFSP
DSKQLASGGW DKRAIVWEVQ SGRRVHLLVG HCDSIQSSDF SPTSDSLATG SWDSTVHIWD
LRASTPVVSY HNLEGHTGNI SCLCYSASGL LASGSWDKTI CVWKPTTNNL PLQLKGHTIW
VNSLAFSPDE LKLASAGYSR TVKVWDCLTG KCLETLKGML DVAHACIFTP DGKLLVSGAA
VTR
