ID   WDR55_AEDAE             Reviewed;         468 AA.
AC   Q0IF90;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=AAEL006422;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH477389; EAT41996.1; -; Genomic_DNA.
DR   RefSeq; XP_001657781.1; XM_001657731.1.
DR   AlphaFoldDB; Q0IF90; -.
DR   SMR; Q0IF90; -.
DR   STRING; 7159.AAEL006422-PA; -.
DR   GeneID; 5567960; -.
DR   KEGG; aag:5567960; -.
DR   VEuPathDB; VectorBase:AAEL024812; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_1_1; -.
DR   InParanoid; Q0IF90; -.
DR   OMA; QTHHPHD; -.
DR   PhylomeDB; Q0IF90; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..468
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373957"
FT   REPEAT          134..173
FT                   /note="WD 1"
FT   REPEAT          178..217
FT                   /note="WD 2"
FT   REPEAT          221..259
FT                   /note="WD 3"
FT   REPEAT          262..301
FT                   /note="WD 4"
FT   REPEAT          304..343
FT                   /note="WD 5"
FT   REPEAT          388..427
FT                   /note="WD 6"
FT   REGION          1..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..88
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  52556 MW;  DA74CB860FC87A4B CRC64;
     MRNFNSPKFG HSMGDDSDDD DFDSGTEPEF LVEPYVLEEF PITEEIEEIE GDDEEYNPNE
     EIGTSSSDDE DDSDDSDSDK EQENGGEDGE DSSTTNTVPK RVIDDYDEDM EEDEVIKAII
     TEIKKPRSKP PDIKTEDFVT DLCFHPDQDL LAVGTTTGDV IVYKFTNDEC TIVNTHETHT
     KSVRDVEFNA DGDLLISTAR DRSIMVTDVE TGKLKRFWDD AHEEPVYTMS MITEHTFATG
     DDGGVLKLWD LRQKDPVFKL KEVEDFISCI ITNEQKKYLL MTSGDGYLTT INIPQRKMYV
     QSEPYEEELT CMGVFRRDSK LVVGSSKGNF YTFNWGQFGY HCDAFIGPKA GVNKMVPITE
     RIAVTGGEDG ILRAMHLVPG RVLGIVGQHS LAVETMDINS TGELIASSSH DNDIRFWNIK
     YFEEFDDIKY NSKPDKKAMT HNLPSSKQTN AADFFSGLAG DQSGAEGD