ID   WDR55_DICDI             Reviewed;         408 AA.
AC   Q54SA5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   Name=wdr55; ORFNames=DDB_G0282573;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; AAFI02000047; EAL66146.1; -; Genomic_DNA.
DR   RefSeq; XP_640134.1; XM_635042.1.
DR   AlphaFoldDB; Q54SA5; -.
DR   SMR; Q54SA5; -.
DR   STRING; 44689.DDB0304577; -.
DR   PaxDb; Q54SA5; -.
DR   EnsemblProtists; EAL66146; EAL66146; DDB_G0282573.
DR   GeneID; 8623671; -.
DR   KEGG; ddi:DDB_G0282573; -.
DR   dictyBase; DDB_G0282573; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_2_1_1; -.
DR   InParanoid; Q54SA5; -.
DR   OMA; QTHHPHD; -.
DR   PhylomeDB; Q54SA5; -.
DR   PRO; PR:Q54SA5; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..408
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373969"
FT   REPEAT          17..56
FT                   /note="WD 1"
FT   REPEAT          61..100
FT                   /note="WD 2"
FT   REPEAT          104..141
FT                   /note="WD 3"
FT   REPEAT          144..183
FT                   /note="WD 4"
FT   REPEAT          186..224
FT                   /note="WD 5"
FT   REPEAT          227..265
FT                   /note="WD 6"
FT   REPEAT          268..308
FT                   /note="WD 7"
FT   REGION          308..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        308..341
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        349..371
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..408
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   408 AA;  46002 MW;  767648BC732D0D28 CRC64;
     MDTSSEGDHE LAPNDISFNT IPFSLNFHPT EDLLVVSDAE GRLKLFKYSL DENEVKLSLR
     PHQSGCRQAN FSSDGKYIFT ASSDCSMKVI DINTGSILYT REEAHDYPIN CLVSKEFMVF
     TGDDEGTIKV WDMRQQNIVC EFQEHGDFIS DITTIDDRHI AATSGDGGVS IYNFVRKSMD
     DISEKSDNEL LSCLSLDNGQ KLVCGSQDGS ILIYDRNNLE NVKKFAGHPQ SVDALVKVNN
     NTFFSGSSDG IIRFIGLRPK KLLGVVGEHS TFPIERMAIS RDNRYLGSIS HDFSLKFWNV
     ASFYEEDESE DADSANANAN EIENDDDDDD DDDEIEDIEN ATKVDDDSGS EMGDDDDDDD
     DEEQEEEEES SSDEDIKRKK PQQNPIKAQQ IEKQKQKQNQ KRSFFKDL