ID   WDR55_DROAN             Reviewed;         481 AA.
AC   B3M1G0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GF18399;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH902617; EDV43251.1; -; Genomic_DNA.
DR   RefSeq; XP_001954690.1; XM_001954654.2.
DR   AlphaFoldDB; B3M1G0; -.
DR   SMR; B3M1G0; -.
DR   STRING; 7217.FBpp0121591; -.
DR   EnsemblMetazoa; FBtr0123099; FBpp0121591; FBgn0095417.
DR   GeneID; 6501174; -.
DR   KEGG; dan:6501174; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   InParanoid; B3M1G0; -.
DR   OMA; NERMEYL; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; B3M1G0; -.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:EnsemblMetazoa.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..481
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373958"
FT   REPEAT          144..183
FT                   /note="WD 1"
FT   REPEAT          188..227
FT                   /note="WD 2"
FT   REPEAT          231..269
FT                   /note="WD 3"
FT   REPEAT          272..311
FT                   /note="WD 4"
FT   REPEAT          314..353
FT                   /note="WD 5"
FT   REPEAT          398..437
FT                   /note="WD 6"
FT   REGION          1..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..82
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  53978 MW;  644726F75D69EA89 CRC64;
     MHTHNHFKTP SDAEEVDDLD DEMVMGVIAE IEQEVLFESD SDDDGFGAEQ LGAPPPDDDN
     DQISSSDDSF DPNAEDSDSD DSMQHEEQAQ ATSAKRRKDD DGPSGSNRDV ETNFDLDLED
     ETDETVRAII AAIKKPRSAP PEIKLEDFVT DISFHPERNI IALATIIGDV HLYEYANEGN
     KLIRTIEVHS KACRDVEFTE DGRNLLTCSK DKCVMVTDME TEKLKKLYET AHDDAINTLH
     VLNENLFATG DDAGTVKLWD LRTKQHVFEL KQIDDQVTQL LSNEQNTLLL ATSADGYLTT
     FNIPGRKLYV QSEPYEEELN CMGIYRGDSK LVVGTSKGKL YSYNWGSFGY HCDMYPGIKS
     PISLMIPITD RIACVAGEDG NIRACHITPY RNLGVVGQHN MPIEALDVNS TGELLASSSH
     NNDVRFWNVK YFEDFGDIKY NEKHNAYKEQ RHNLPSSKCT NTGDFFADLA KQEDDEDDDA
     T