ID   WDR55_DROER             Reviewed;         498 AA.
AC   B3P4F8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GG18443;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14021-0224.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH954181; EDV49473.1; -; Genomic_DNA.
DR   RefSeq; XP_001980515.1; XM_001980479.2.
DR   AlphaFoldDB; B3P4F8; -.
DR   SMR; B3P4F8; -.
DR   STRING; 7220.FBpp0136989; -.
DR   EnsemblMetazoa; FBtr0138497; FBpp0136989; FBgn0110658.
DR   GeneID; 6553820; -.
DR   KEGG; der:6553820; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   OMA; QTHHPHD; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; B3P4F8; -.
DR   Proteomes; UP000008711; Unassembled WGS sequence.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:EnsemblMetazoa.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Repeat; WD repeat.
FT   CHAIN           1..498
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373959"
FT   REPEAT          155..194
FT                   /note="WD 1"
FT   REPEAT          199..238
FT                   /note="WD 2"
FT   REPEAT          242..280
FT                   /note="WD 3"
FT   REPEAT          283..322
FT                   /note="WD 4"
FT   REPEAT          325..364
FT                   /note="WD 5"
FT   REPEAT          409..448
FT                   /note="WD 6"
FT   REGION          1..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..78
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..93
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        102..116
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  55415 MW;  0F0784099DB7BA32 CRC64;
     MHTHNNFKTP SDEDELDDLD EDMVVGVIAE IEQEVLNESD SDNDEYDLVE MGAPVPDNDG
     DSSYDGNESI SSDDSFDPNA ADSDSDDSML DDAGDDASAG GATSSKRRKD DDNPSGSNRQ
     SEATFDLDED DETDETVRAM IAAIKKPRSA PPEIKLEDFI TDICFHPDRD IIALATIIGD
     VHLYEYDNEA NKLLRTIEVH SKACRDVEFT EDGRFLLTCS KDKCVMVTDM ETEKLKKLYE
     TAHDDAINTL HVLNENLFAT GDDAGTVKLW DLRTKNAIFE LKELEDQITQ LTTNDQSKLL
     LATSADGYLT TFNIAARKMY VQSEPYEEEL SCMGIYRGDS KLVVGTSKGR LYTYNWGQFG
     YHCDMYPGIK SPISLMIPIT DRIACVAGED GNIRACHIAP YRNLGVVGQH NMPIESLDVN
     SNGELIASSS HNNDVRFWNV KYFEDFGDIK YNEKHNAYKE QRHNLPSSKC SNASDFFADL
     TKEDADDDDA GAGPSNMA