ID   WDR55_DROGR             Reviewed;         503 AA.
AC   B4JSW8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GH23127;
OS   Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH916373; EDV94858.1; -; Genomic_DNA.
DR   RefSeq; XP_001994122.1; XM_001994086.1.
DR   AlphaFoldDB; B4JSW8; -.
DR   SMR; B4JSW8; -.
DR   STRING; 7222.FBpp0157033; -.
DR   EnsemblMetazoa; FBtr0158541; FBpp0157033; FBgn0130584.
DR   GeneID; 6567888; -.
DR   KEGG; dgr:6567888; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   InParanoid; B4JSW8; -.
DR   OMA; QTHHPHD; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; B4JSW8; -.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..503
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373960"
FT   REPEAT          154..193
FT                   /note="WD 1"
FT   REPEAT          198..237
FT                   /note="WD 2"
FT   REPEAT          241..279
FT                   /note="WD 3"
FT   REPEAT          282..321
FT                   /note="WD 4"
FT   REPEAT          324..363
FT                   /note="WD 5"
FT   REPEAT          408..447
FT                   /note="WD 6"
FT   REGION          1..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          476..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..49
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   503 AA;  55891 MW;  18E56548F2A7B5EF CRC64;
     MHTHEHFKSP TNEDELDDTD DDMVAGVIAE IEQDVLNESE SDDDEYDLAD MGALVQHQAA
     SSSDDSISSD GSFDPNAEDT DSDDSMIDEV ASAGASSAKR RKEQSADDGA GPSGSDPSGV
     SDYSHLDEDD ETDETVRAMI AAIKKTRSAP PEIKLEDFIT DICFHPERDI IALATIIGDV
     HLYEYGNEEN KLLRTIEVHA KACRDVEFTE DGRSLITCSK DKCVMVTDME TEKLKKLYET
     AHDDAINKLF VLDERLFATG DDAGTVKLWD FRTKDAIFEL KEVEDQITQM LTNEQNKLLL
     ATSADGYLTT YNIGARKLYV QSEPYEEELS CMGIYRGNSK LVAGTSKGRL YTYNWGYFGY
     HCDMYPGIKS PISLMVPITD RIACVAGEDG NIRACHIAPY RNLGVVGQHN MPIESLDINC
     SGELLASSSH NNDVRFWNVK YFEDFGDIKY NEKHNAYKEK RHNLPSSKCT NASDFFADMT
     KEQDDDDNGG QDNNTGAGPS NIT