WDR55_DROMO
ID WDR55_DROMO Reviewed; 506 AA.
AC B4KE10;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=WD repeat-containing protein 55 homolog;
GN ORFNames=GI10299;
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDW16031.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CH933806; EDW16031.1; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_002000570.2; XM_002000534.2.
DR AlphaFoldDB; B4KE10; -.
DR SMR; B4KE10; -.
DR STRING; 7230.FBpp0159516; -.
DR GeneID; 6574527; -.
DR KEGG; dmo:Dmoj_GI10299; -.
DR eggNOG; KOG2444; Eukaryota.
DR InParanoid; B4KE10; -.
DR OMA; QTHHPHD; -.
DR PhylomeDB; B4KE10; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:EnsemblMetazoa.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..506
FT /note="WD repeat-containing protein 55 homolog"
FT /id="PRO_0000373962"
FT REPEAT 156..195
FT /note="WD 1"
FT REPEAT 200..239
FT /note="WD 2"
FT REPEAT 243..281
FT /note="WD 3"
FT REPEAT 284..323
FT /note="WD 4"
FT REPEAT 326..365
FT /note="WD 5"
FT REPEAT 410..449
FT /note="WD 6"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 33..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..50
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 56352 MW; 4790A43FDA087897 CRC64;
MHRHDCFKTP ADEDELDDID DDMVVGVIAE IEQEVLNESE SDDDEYDLAD MGAPEPERND
GNISSNESIS SDGSFDPNAE DTDSDDSMLD EAATAGASIA KRRKEQNAMD GAEPSGSGPS
GSGDYSHLDE DDETDETVRA MIAAIKKPRS APPEIRLEDF ITDICFHPER DIIALATIIG
DVHLYEYGNE ENKLLRSIEV HAKACRDVEF TEDGRSLITC SKDKCVMVTD METEKLKKLY
ETAHDDAINK LHVLDERLFA TGDDAGTVKL WDFRTKDAIF ELKEVEDQIT QMLTNEQNKL
LLATSADGYL TTFNIGARKL YVQSEPYEEE LNCMGIYRGS SKLVVGTSKG RLYTYNWGYF
GYHCDMYPGV KSPISLMIPI TDRIACVAGE DGNIRACHIA PYRNLGVVGQ HNMPIESLDI
NSSGELLASS SHNNDVRFWN VKYFEDFGDI KYNEKHNAYK DKRHNLPSSK CTNASDFFAD
MTKEQDDDDN DDGGNNTTAA GSNNVT
