ID   WDR55_DROVI             Reviewed;         504 AA.
AC   B4M4W4;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GJ10153;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH940652; EDW59675.1; -; Genomic_DNA.
DR   RefSeq; XP_002056563.2; XM_002056527.2.
DR   AlphaFoldDB; B4M4W4; -.
DR   SMR; B4M4W4; -.
DR   STRING; 7244.FBpp0224570; -.
DR   GeneID; 6632928; -.
DR   KEGG; dvi:6632928; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   InParanoid; B4M4W4; -.
DR   OMA; QTHHPHD; -.
DR   PhylomeDB; B4M4W4; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..504
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373966"
FT   REPEAT          156..195
FT                   /note="WD 1"
FT   REPEAT          200..239
FT                   /note="WD 2"
FT   REPEAT          243..281
FT                   /note="WD 3"
FT   REPEAT          284..323
FT                   /note="WD 4"
FT   REPEAT          326..365
FT                   /note="WD 5"
FT   REPEAT          410..449
FT                   /note="WD 6"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          33..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..50
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   504 AA;  55802 MW;  5E9D45FA54DFDC86 CRC64;
     MDRHEHFKAP ANEDELDDID DDMVVGVIAE IEQEVLNESE SDDDEYDLVD MGAPEPQQAD
     GHSSSNESIS SDGSFDPNAE DSDSDDSMID EAASGGASSA KRRKEQTATD GVGASGSGAS
     GGADYSHLDD DDETDETVRA IIAAIKKPRS APPEIKLEDF ITDICFHPDR DIIALATIIG
     DVHLYEYGNE ENKLLRTIEV HAKACRDVEF TEDGRSLITC SKDKCVMVTD METEKLKKLY
     ETAHDDAINK LHVLDERLFA TGDDAGTVKL WDFRTKDAIF ELKEVEDQIT QMLTNEQNKL
     LLATSADGYL TTYNIGARKL YVQSEPYEEE LNCMGIYRGS SKLVAGTSKG RLYTYNWGYF
     GYHCDMYPGI KSPISLMIPI TDRIACVAGE DGNIRACHIA PYRNLGVVGQ HNMPIESLDI
     NCSGELLASS SHNNDVRFWN VKYFEDFGDI KYNEKHNAYK EKRHNLPSSK CTNASDFFAD
     MTKDQDDDDN DGGNDTAAGP SNVT