ID   WDR55_DROWI             Reviewed;         504 AA.
AC   B4N984;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GK12179;
OS   Drosophila willistoni (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7260;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14030-0811.24;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CH964232; EDW81631.1; -; Genomic_DNA.
DR   RefSeq; XP_002070645.1; XM_002070609.2.
DR   AlphaFoldDB; B4N984; -.
DR   SMR; B4N984; -.
DR   STRING; 7260.FBpp0241322; -.
DR   EnsemblMetazoa; FBtr0242830; FBpp0241322; FBgn0214190.
DR   GeneID; 6647877; -.
DR   KEGG; dwi:6647877; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   InParanoid; B4N984; -.
DR   OMA; QTHHPHD; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; B4N984; -.
DR   Proteomes; UP000007798; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..504
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373967"
FT   REPEAT          158..197
FT                   /note="WD 1"
FT   REPEAT          202..241
FT                   /note="WD 2"
FT   REPEAT          245..283
FT                   /note="WD 3"
FT   REPEAT          286..325
FT                   /note="WD 4"
FT   REPEAT          328..367
FT                   /note="WD 5"
FT   REPEAT          412..451
FT                   /note="WD 6"
FT   REGION          32..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          484..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..48
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..93
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..115
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   504 AA;  56391 MW;  A92D729C1316379E CRC64;
     MHTHELFKTP LEEDEVEVSE DDVVGFIAEI EQEVVNESDS EIGEYDLGDD IGAPEPFERA
     AANAEDSISS DGSFNPNDED SDTDSDDSML DEPDEAAVGG ASKAKRRKDD DGPSGSSNRN
     QDSDGNAFDM DEDDETDETV RAIIAAIKKP RSAPPEIKLE DFITDICFHP ERHIIALATI
     IGDVHLYEYS NEENKLLKTI EVHAKACRDV EFTEDGRSLI TCSKDKSVMI TDMETEKLKK
     LYETAHDDAI NKLLVLDERL FASGDDSGTV KLWDFRTKDS IFELKEIEDQ VTQMITNDQK
     KLLLATSADG YLTTFNIGAR KLYVQSEPYE EELNCMGIYR GNSKLVVGTS KGRLYSYNWG
     YFGYHCDMYP GIKSPISLMI PITERIACVA GEDGNIRACH ITPYRNLGVV GQHNMPIESM
     DINTNGELLA SSSHNNDVRF WNVKYFEDFG DIKYNEKHNA YKDKRHNLPS SKCTNASDFF
     ADLAKEDNND NENDDATAGP SNTT