ID   WDR55_DROYA             Reviewed;         499 AA.
AC   B4PU14;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=WD repeat-containing protein 55 homolog;
GN   ORFNames=GE24201;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the WD repeat WDR55 family. {ECO:0000305}.
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DR   EMBL; CM000160; EDW97664.1; -; Genomic_DNA.
DR   RefSeq; XP_002097952.1; XM_002097916.2.
DR   AlphaFoldDB; B4PU14; -.
DR   SMR; B4PU14; -.
DR   STRING; 7245.FBpp0269211; -.
DR   EnsemblMetazoa; FBtr0270719; FBpp0269211; FBgn0241332.
DR   GeneID; 6537396; -.
DR   KEGG; dya:Dyak_GE24201; -.
DR   eggNOG; KOG2444; Eukaryota.
DR   HOGENOM; CLU_035848_1_0_1; -.
DR   OMA; QTHHPHD; -.
DR   OrthoDB; 1173229at2759; -.
DR   PhylomeDB; B4PU14; -.
DR   Proteomes; UP000002282; Chromosome 3R.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:EnsemblMetazoa.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR024977; Apc4_WD40_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Repeat; WD repeat.
FT   CHAIN           1..499
FT                   /note="WD repeat-containing protein 55 homolog"
FT                   /id="PRO_0000373968"
FT   REPEAT          154..193
FT                   /note="WD 1"
FT   REPEAT          198..237
FT                   /note="WD 2"
FT   REPEAT          241..279
FT                   /note="WD 3"
FT   REPEAT          282..321
FT                   /note="WD 4"
FT   REPEAT          324..363
FT                   /note="WD 5"
FT   REPEAT          408..447
FT                   /note="WD 6"
FT   REGION          1..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          480..499
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..27
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..78
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   499 AA;  55518 MW;  F5AE8C6D3E19E077 CRC64;
     MHTHNNFKTP SDEDELDDLD EDMVVGVIAE IEQEVLNESD SDNDEYDLVD MGAPVPENDG
     DSSYDGNESI SSDDSFDPNA ADSDSDDSML DDAGGASAGG ATSAKRRKDD DNPSGSNRQS
     EATFDLDVDD ETDETVRAMI AAIKKPRSAP PEIKLEDFIT DICFHPDRDI IALATIIGDV
     HLYEYDNEAN KLLRTIEVHS KACRDVEFTE DGRFLLTCSK DKCVMVTDME TEKLKKLYET
     AHDDAINTLH VLNENLFATG DDAGTVKLWD LRTKNAIFEL KELEDQITQL TTNDQNKLLL
     ATSADGYLTT FNIAARKMYV QSEPYEEELS CMGIYRGDSK LVVGTSKGRL YTYNWGQFGY
     HCDMYPGIKS PISLMIPITD RIACLAGEDG NIRACHIAPY RNLGVVGQHN MPIESLDVNS
     SGELIASSSH NNDVRFWNVK YFEDFGDIKY NEKHNAYKEQ RHNLPSSKCS NASDFFADLT
     KEDADDDDHD PSAGPSNMA