ID   WDR61_DICDI             Reviewed;         299 AA.
AC   Q54S59;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=WD repeat-containing protein 61 homolog;
GN   Name=wdr61; ORFNames=DDB_G0282793;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000047; EAL66256.1; -; Genomic_DNA.
DR   RefSeq; XP_640180.1; XM_635088.1.
DR   AlphaFoldDB; Q54S59; -.
DR   SMR; Q54S59; -.
DR   STRING; 44689.DDB0267163; -.
DR   PaxDb; Q54S59; -.
DR   EnsemblProtists; EAL66256; EAL66256; DDB_G0282793.
DR   GeneID; 8623719; -.
DR   KEGG; ddi:DDB_G0282793; -.
DR   dictyBase; DDB_G0282793; wdr61.
DR   eggNOG; KOG4155; Eukaryota.
DR   HOGENOM; CLU_000288_57_11_1; -.
DR   InParanoid; Q54S59; -.
DR   OMA; VGFSPCN; -.
DR   PhylomeDB; Q54S59; -.
DR   Reactome; R-DDI-429958; mRNA decay by 3' to 5' exoribonuclease.
DR   Reactome; R-DDI-674695; RNA Polymerase II Pre-transcription Events.
DR   Reactome; R-DDI-75955; RNA Polymerase II Transcription Elongation.
DR   PRO; PR:Q54S59; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016593; C:Cdc73/Paf1 complex; IBA:GO_Central.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..299
FT                   /note="WD repeat-containing protein 61 homolog"
FT                   /id="PRO_0000328583"
FT   REPEAT          11..48
FT                   /note="WD 1"
FT   REPEAT          54..93
FT                   /note="WD 2"
FT   REPEAT          96..135
FT                   /note="WD 3"
FT   REPEAT          138..177
FT                   /note="WD 4"
FT   REPEAT          180..219
FT                   /note="WD 5"
FT   REPEAT          223..263
FT                   /note="WD 6"
FT   REPEAT          266..299
FT                   /note="WD 7"
SQ   SEQUENCE   299 AA;  32355 MW;  58061042B42ECCCD CRC64;
     MFQFGKKITG AHEDGIWCVK WQGDIIATGG MGTKVKTWHG NQPQFLTERK VFDKHILGVT
     SLDIDIGARY LATGGMDGTV RLFDLSTNTL HKTIDSGPLG CLKIGFLNSA NNLVSVSESG
     NISIYSVETG EKLRSISNTN KQVLTMAISP NNEQIAVAGL DGTVLCYDVE SGRRVSEIKA
     HGVPIRSLCF SSDSKTIFTG AEDSQIRLHD PNSSNPYIAS LLGHSSFIFS LVASSNGDLL
     ASSGSIDRKV CIWDIKTRKL DSSFTAHADQ TWDLAFSPDS TKLVSVSDDC SIHSYALKQ