WDR93_MOUSE
ID WDR93_MOUSE Reviewed; 695 AA.
AC Q402B2; B9EKH5;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=WD repeat-containing protein 93;
DE AltName: Full=Protein MA0035;
GN Name=Wdr93;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=C57BL/6J; TISSUE=Testis;
RA Ijiri T.W., Nagase T., Matsuda Y.;
RT "Isolation and characterization of novel testis-specific genes from mouse
RT pachytene spermatocyte-enriched cDNA library.";
RL Reprod. Med. Biol. 4:231-237(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- TISSUE SPECIFICITY: Testis-specific. Expressed in spermatogonia,
CC spermatocytes and spermatids. {ECO:0000269|Ref.1}.
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DR EMBL; AB205021; BAE19974.1; -; mRNA.
DR EMBL; BC150920; AAI50921.1; -; mRNA.
DR CCDS; CCDS39992.1; -.
DR RefSeq; NP_001033016.1; NM_001037927.1.
DR RefSeq; XP_006541110.1; XM_006541047.3.
DR RefSeq; XP_006541112.1; XM_006541049.3.
DR AlphaFoldDB; Q402B2; -.
DR STRING; 10090.ENSMUSP00000037467; -.
DR PhosphoSitePlus; Q402B2; -.
DR jPOST; Q402B2; -.
DR PaxDb; Q402B2; -.
DR PRIDE; Q402B2; -.
DR ProteomicsDB; 299761; -.
DR Antibodypedia; 54557; 66 antibodies from 16 providers.
DR Ensembl; ENSMUST00000035622; ENSMUSP00000037467; ENSMUSG00000039099.
DR GeneID; 626359; -.
DR KEGG; mmu:626359; -.
DR UCSC; uc009hza.1; mouse.
DR CTD; 56964; -.
DR MGI; MGI:3646885; Wdr93.
DR VEuPathDB; HostDB:ENSMUSG00000039099; -.
DR eggNOG; ENOG502QW2J; Eukaryota.
DR GeneTree; ENSGT00390000009995; -.
DR HOGENOM; CLU_025331_0_0_1; -.
DR InParanoid; Q402B2; -.
DR OMA; VPWKPMF; -.
DR OrthoDB; 900109at2759; -.
DR PhylomeDB; Q402B2; -.
DR TreeFam; TF336347; -.
DR BioGRID-ORCS; 626359; 2 hits in 73 CRISPR screens.
DR PRO; PR:Q402B2; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q402B2; protein.
DR Bgee; ENSMUSG00000039099; Expressed in spermatocyte and 38 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR006885; NADH_UbQ_FeS_4_mit.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR12219; PTHR12219; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; WD repeat.
FT CHAIN 1..695
FT /note="WD repeat-containing protein 93"
FT /id="PRO_0000319604"
FT REPEAT 421..460
FT /note="WD"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 695 AA; 78911 MW; 01E1DF11A2B98964 CRC64;
MSSFKGNQAQ KRRLSVFPKG PLEIPSPTEA DWPKDDEKDF VFKDLDQELD SLPQPYRMIN
KLVDHLFNRS WEIIEERDSL REVEKNWIVP AIYHPVAEIQ LDKMPGGMAV SHDYLFIGGL
KGFSIYNLHN CKRIYVLEKF KADVISIWAT DLGNDVLIVP IDEMGIVRLF YLCKDSLYHI
KAINEVDDSS KQSTCLKMEI SQNGDFAAFL FQGAGDVWLE VYKLPKEIWL KEMEHPQSTL
NQKKKAKQLQ LSTPDSAVTE SIETSSGPSV SSNSVQDLNI SFKSDLKLSL PVFVMKIKPP
KPIAGTTFKS PLEVFAKVED YVGLGSGQNH FIKDVQWEQH METFYASYKK HLEGEWEEEP
LSMATFHFFY TNSLTTMSMD VKSSSGIACV LGIHWNGRHN LFFYSLNKTQ KDKTEYENVW
PCAAPIVMSQ ISSFSSYLAL VCEDGVLILW DLAEGFLFGV VALPEGCFCQ SIHFLRFFLV
HEGQNVYPDY PVKFEVMCVV LCTDASLHLV TASGTQGPTS KVLVGRPVMH MEEAICAVAP
VPALPGMVLI FSRSQSVTLM DVAKAEVLCA FSAPTCHPQA LPWKPLFAVS PHHPYFLLHG
AHPHGQTTST EDPKKSTDSV FYFNFEDYLL LKDISKKCTI SQMAVNFSQM LPVEKRCEQV
FQKSIQMTKT QMKGREQWSR LRKYSIMLQK ELLKR