ID   WDY_CULQU               Reviewed;        1033 AA.
AC   B0WYR6; B0WYR7;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 2.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=WD repeat-containing protein on Y chromosome {ECO:0000250|UniProtKB:B4F7L9};
DE            Short=WD40 Y {ECO:0000250|UniProtKB:B4F7L9};
GN   Name=WDY {ECO:0000250|UniProtKB:B4F7L9}; ORFNames=CPIJ012294;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000312|EMBL:EDS37176.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000312|EMBL:EDS37176.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDS37176.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EDS37177.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS232197; EDS37176.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DS232197; EDS37177.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001862538.1; XM_001862503.1.
DR   RefSeq; XP_001862539.1; XM_001862504.1.
DR   AlphaFoldDB; B0WYR6; -.
DR   STRING; 7176.CPIJ012294-PA; -.
DR   GeneID; 6045137; -.
DR   KEGG; cqu:CpipJ_CPIJ012294; -.
DR   KEGG; cqu:CpipJ_CPIJ012295; -.
DR   VEuPathDB; VectorBase:CPIJ012294; -.
DR   VEuPathDB; VectorBase:CPIJ012295; -.
DR   VEuPathDB; VectorBase:CQUJHB002787; -.
DR   eggNOG; KOG0273; Eukaryota.
DR   HOGENOM; CLU_006741_0_1_1; -.
DR   InParanoid; B0WYR6; -.
DR   OrthoDB; 1637853at2759; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..1033
FT                   /note="WD repeat-containing protein on Y chromosome"
FT                   /id="PRO_0000377420"
FT   REPEAT          54..96
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          132..172
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          181..220
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          353..392
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          396..435
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          485..524
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          537..578
FT                   /note="WD 7"
FT                   /evidence="ECO:0000255"
FT   REPEAT          625..667
FT                   /note="WD 8"
FT                   /evidence="ECO:0000255"
FT   REPEAT          719..764
FT                   /note="WD 9"
FT                   /evidence="ECO:0000255"
FT   REPEAT          771..810
FT                   /note="WD 10"
FT                   /evidence="ECO:0000255"
FT   REPEAT          845..884
FT                   /note="WD 11"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1033 AA;  117548 MW;  4F899A4F435AA7ED CRC64;
     MERKSTLSSP GSSLESVDHS QPQLLHRYLT RENVQHLHQL FDQRKQLLPD ELRAELFVLT
     GVRFSDEEFE TLFMKINTDR DNFCQWDELI SYLILGFHND DPLAVQESLD LPISLDMSVK
     LGRQTYPVIK IEYSPMVSYD GTVNWSQGFW ATSTQEAVIN FWKRDWKHEK TGKAFSVDLK
     RAKTWILDTA VLPDLNYFCV ACLEHELRIY DIIGSGFTLK IIVNRIPNPI NALKYHFSAS
     TRSKLIMGDY KGVLRVVEFY PERKEPFKFD AASTVTRLSF RDLLNGSYPQ MECVDYGRLL
     PDIVRQLQFV EPTYSFLACS ENDPLAPSGS RKKLYTSVII QHLTKLDKIT KIKVPKGVTC
     FAYDHVKDFL VTGGPDGELR MWDIRRPENP VASLSGHNAG VVFMFLQDGS QKIYSMDTKK
     IVKIWDVLNR ILIQTYSQFS TTLYKTVPAC AYYNDLNREL VIGANKVLSA PCCPKIPLEV
     TDGESHTQPI SVLLYNPLFK VLISCGLDSY IIVWDHTMNR KLTIITDAHT QVVNGLLEQV
     QITAACFDPK LQLLLTGARD GTLKVWNFNS GSCMSSMSIQ EGCEVTAVFW EPTSILAMGW
     NHAVVEFPVG TTGMDFPRGI DWQKLHSDDI LCASVTHSEP KAIATCSYTG EIVFWLMETG
     QPYQRFNAAK PQQKIPVNAM TTKIGKPKRR SRMSVFMPQE QLRQRRLTRI VMPVKAEQLR
     QLTIHELLFL ESRPMHPEVG TLLSSLDTGV IQVYSHHVDG GFLGSFNAVH MAGDRVVSMT
     TDPYNKFLFT GSYLGYVKTW LLEASFNRAA LKMQFPFLLD DIIPGRAKRS VANQPLPWLL
     NSYQAHRNCI TALSYIPATK LLLSASSDHT IRIWSLAGRY IGLLGSPVKW ATIDADVPIP
     KEYGFRIPPD LQREVSFTTA QVLRGGERAI KLKSRILQEA SERRRTEAVE TYGQPLEDPI
     IKPEVFPYGY RAGFVHDAKM DYSFRETPIF EHLSIQNLTK LKVVDSKRVV EKVEGLDFSN
     DGDRIDTYHE RNI