ID   WDY_DROAN               Reviewed;        1064 AA.
AC   B0FXQ5;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 2.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=WD repeat-containing protein on Y chromosome {ECO:0000303|PubMed:19011613, ECO:0000312|EMBL:ABY59794.1};
DE            Short=WD40 Y {ECO:0000303|PubMed:19011613};
GN   Name=WDY {ECO:0000312|EMBL:ABY59794.1};
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1] {ECO:0000312|EMBL:ABY59794.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=19011613; DOI=10.1038/nature07463;
RA   Koerich L.B., Wang X., Clark A.G., Carvalho A.B.;
RT   "Low conservation of gene content in the Drosophila Y chromosome.";
RL   Nature 456:949-951(2008).
RN   [2] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13 {ECO:0000269|PubMed:17994087};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABY59794.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; EU362855; ABY59794.1; ALT_INIT; mRNA.
DR   EMBL; AAPP01000240; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAPP01011194; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAPP01017377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAPP01018149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; B0FXQ5; -.
DR   PRIDE; B0FXQ5; -.
DR   EnsemblMetazoa; FBtr0391054; FBpp0350538; FBgn0275370.
DR   InParanoid; B0FXQ5; -.
DR   OrthoDB; 1272807at2759; -.
DR   ChiTaRS; WDY; fly.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   SUPFAM; SSF50998; SSF50998; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..1064
FT                   /note="WD repeat-containing protein on Y chromosome"
FT                   /id="PRO_0000377421"
FT   REPEAT          150..194
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          317..356
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          360..399
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          450..489
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          502..541
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          589..629
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          742..781
FT                   /note="WD 7"
FT                   /evidence="ECO:0000255"
FT   REPEAT          825..864
FT                   /note="WD 8"
FT                   /evidence="ECO:0000255"
FT   REGION          1022..1044
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1064 AA;  121415 MW;  720EC9BDCA13CE4D CRC64;
     MPMLIQKSEV EYQTISSTQS HLAEEQSERL HRCISKEQLE KLHEAFLNAP ERQVGIDDLR
     VMLEDLDITF NDSMYTRLFL KINQNRDFRV DWNEFVSYLI FGFQEEDPSS QKESLILPIS
     VPPMVRKSEH RSAICCLALL KAKSDQVPIE EVTETVNFSF GGEDSPEASG MWVTASHEGM
     MRFWTSHMEP IRTASSESIH LNYAFYNNGK VHSKLILGDY AGNVRILSYS PHLRGPFQAK
     PGAALIEVVW SDVLKGKIPQ FVPKEYISLH NEMISCVYFS LHMNALFASA EYRNTKKYRG
     RCPGMIMVTY DERSNFRIPL GVSTFFVAES HNIVVTGGPD TFVRIWDVYI PTEPSAILTG
     HNGGIVLVFV QPEENKVYSV DYQKIIKVWD LQEHTLLQTY GDLVRLIHHS ETDLTYYYHS
     HLRELVVAGR KLISIKCCPR VRVDLTDGNT HAAPVSVVLY NRLFRNIVTC GLDSYIIVWD
     PWTGRRKIIM KSCHTKMIYG EIIDIEITAA CFDPLEQFLL TGARDGSLKI WNYNNAVVVR
     NMSIMPDQEV TSVIWVVDRI LAMGWDRQVT EFNDVVGREY GDPKKWPKFH TDDITCADVK
     LGEGVVTATY SGEIIFWKLE TGQPYRRYSV MDPTRFIELK LTAEEEKSLR RSKRLASRPT
     HTGIHGLQMS RAGRSTVTNR PEDNRDYGAN IPISVQAVLF LQTRPQTLKH GSVFISLDTG
     YIQVYSHHQR GGYMMEFLAV HKTGDCVLTM CTDRKNRFLY TGTAFGYVKI WYIVNFCVPA
     SEKTHVCMPK LRLEFIFLRK ELFLTRAKRA IRNQPEPLLV SSYKGHLKAI NSIAFINLPK
     IVFTGSHDYS CRLWTQGGRY LGTLGTVLPW SKLTPFERAG DDSQTYRMPP DIKKVASSTT
     LKVISGLQAE RMVKRQEGKV TEDRDEDTAQ TEDVTELKRL LDSPIKEPIL GKHFELPGRT
     VLDQHIELDT SQSYIAVYTH LKVHSTEMLE RLPTPAVIGK VQAENYLHHY VPVEGKVDIS
     GSSLNIKQPT RRRSGKTHDP RNIRTAKARL DIGMGLSSSH ASQQ