ID   WDY_DROPS               Reviewed;        1064 AA.
AC   B5DHW4;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 2.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=WD repeat-containing protein on Y chromosome {ECO:0000250|UniProtKB:B4F7L9};
DE            Short=WD40 Y {ECO:0000250|UniProtKB:B4F7L9};
GN   Name=WDY {ECO:0000250|UniProtKB:B4F7L9}; ORFNames=GA25535;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1] {ECO:0000312|EMBL:EDY69891.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDY69891.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CH379059; EDY69891.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; B5DHW4; -.
DR   STRING; 7237.FBpp0279580; -.
DR   eggNOG; KOG0265; Eukaryota.
DR   InParanoid; B5DHW4; -.
DR   ChiTaRS; WDY; fly.
DR   Proteomes; UP000001819; Genome assembly.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF50978; SSF50978; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..1064
FT                   /note="WD repeat-containing protein on Y chromosome"
FT                   /id="PRO_0000377424"
FT   REPEAT          153..197
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          326..365
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          369..408
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          459..498
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          511..550
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          598..638
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          746..785
FT                   /note="WD 7"
FT                   /evidence="ECO:0000255"
FT   REPEAT          827..866
FT                   /note="WD 8"
FT                   /evidence="ECO:0000255"
FT   REGION          914..935
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1023..1064
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1064 AA;  121555 MW;  7B9833C62DFFFC24 CRC64;
     MIFNASQDSK TEIEYQTISS TQTYLAEEQS ERLHNLISKE QLEKLNQAFN ERPDSQVGFD
     DLRGLLLEQD ITFNDAVYNR LFLKINQNRD FMVDWNEFVS YLIFGFQEED PSSQKESLIL
     PISVAPSVRK TEHRSTVCCV ALLKAKSDQV PIEEVTETVN FSFGGEDSPE ASGMWVTASH
     EGMLRFWTSH MEPIRTATSE SSKPHAVYCM SYAFYNNGKV HSKLVLGDYA GNVRILSYSP
     NLRGPFQAKP GAALIEVVWA DVLKGKIPQM IPKEYINLHN EMISCVHYSL HMNALFATAE
     YRNTKKYRGR CPGMIMVTYD ERSNFRVPLG VSTFFVAESH NIVVTGGPDT FVRIWDVYIP
     TEPSAILTGH NGGIVMVFVQ PEENKVYSVD YQKIIKVWDL QEHTLLQTYG ELVRLIHPSE
     TDMTYFYHSH LRELIVAGRK LISIKCCPRV RVDLTDGNTH AAPVSVVLYN RLFRNIVTCG
     LDSYIIVWDP WSGRRKIIMK NCHTKMIYGE IIDIEITAAT FDPLEQFLLT GARDGTLKIW
     NYNNAVVVRN MSIMPDQEVT SVIWVVDRIL AMGWDRQVTE FNDVEGREYG DPKKWSKFHT
     DDITCADVKL GEGVVTATYS GEVIFWKLET GQPYRRYSVM DPTRFIELKL TPEEEKLMRR
     SKRLMSRLGS SRMSRATAIT MPKADDGRDY GQNVPISVQA VLFLQTRPQT IQHGSVFISL
     DTGYIQKVYS HHSRGGYMSQ FLSVHKTGDC VLTMCTDRKN RYIYTGTAFG YIKVWHIVNY
     PEAEKVHVCM PRLRLEFIFM RKEFWVTRAK RVVRHQREPL LVSSYKAHLK AINSIAFINL
     PKIVFRGSHD YSCRLWTQGG RYLGTLGTVL PWSKLSPFER AGSENQVYRL PPDIKKVASS
     TTLKVISGVQ MDRPAKRAEV KAPEDRDEET AQTDDGYDLK KIFDKPLKEP ILGKHFTLPG
     KSVMDQRIDV DTTQSYIAVY THLKVHHTEM LERLPTPAVI SRVAGENYMD HYVPVEGKVD
     LSGSALNIKQ PPRRNVRPND PRNMRMAKTR GDMGPGPSPS QQSE