ID   WETA_ASPOR              Reviewed;         563 AA.
AC   Q2UUM2;
DT   13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Developmental regulatory protein wetA {ECO:0000305};
GN   Name=wetA {ECO:0000303|PubMed:19850144}; ORFNames=AO090009000260;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
RN   [2]
RP   FUNCTION, DISRUPTION PHENOTYPE, AND INDUCTION.
RX   PubMed=19850144; DOI=10.1016/j.fgb.2009.10.004;
RA   Ogawa M., Tokuoka M., Jin F.J., Takahashi T., Koyama Y.;
RT   "Genetic analysis of conidiation regulatory pathways in koji-mold
RT   Aspergillus oryzae.";
RL   Fungal Genet. Biol. 47:10-18(2010).
CC   -!- FUNCTION: BrlA, abaA and wetA are pivotal regulators of conidiophore
CC       development and conidium maturation (PubMed:19850144). They act
CC       individually and together to regulate their own expression and that of
CC       numerous other sporulation-specific genes (By similarity).
CC       {ECO:0000250|UniProtKB:P22022, ECO:0000269|PubMed:19850144}.
CC   -!- INDUCTION: Expression is controlled by abaA (PubMed:19850144).
CC       {ECO:0000269|PubMed:19850144}.
CC   -!- DISRUPTION PHENOTYPE: Loses conidial pigments and exhibits autolytic
CC       phenotype (PubMed:19850144). {ECO:0000269|PubMed:19850144}.
CC   -!- SIMILARITY: Belongs to the wetA family. {ECO:0000305}.
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DR   EMBL; AP007150; BAE54743.1; -; Genomic_DNA.
DR   RefSeq; XP_001816745.1; XM_001816693.1.
DR   AlphaFoldDB; Q2UUM2; -.
DR   STRING; 510516.Q2UUM2; -.
DR   EnsemblFungi; BAE54743; BAE54743; AO090009000260.
DR   GeneID; 5988675; -.
DR   KEGG; aor:AO090009000260; -.
DR   VEuPathDB; FungiDB:AO090009000260; -.
DR   HOGENOM; CLU_030750_0_0_1; -.
DR   OMA; MAYQEAW; -.
DR   Proteomes; UP000006564; Chromosome 1.
DR   GO; GO:0048315; P:conidium formation; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR040112; WetA.
DR   PANTHER; PTHR22934:SF23; PTHR22934:SF23; 2.
PE   2: Evidence at transcript level;
KW   Activator; Conidiation; Reference proteome; Sporulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..563
FT                   /note="Developmental regulatory protein wetA"
FT                   /id="PRO_0000435927"
FT   REGION          54..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          272..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          334..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        54..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..128
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..176
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..307
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..482
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   563 AA;  61439 MW;  2CCC93586FF1B419 CRC64;
     MFAQPFDHSF NNDDLFSQYV NIDGSSTDGN KDVSFPSDFD QFFSLDSLSS NCGEQSPIIS
     TSKQQTHPSP QWAKDFWSLP PDAPSSLGQA PLAFQDTVHP SAVSDLNVNL EASSTTCPAE
     TRSSPTTPPG TPRRKPKSAL VTPKSIQRHR EPNGRRGLQH KQSFSPSLTR PSQFQKGRMA
     YQEAWAHRLQ NLNFLRSADD RFPLSPPPSD ILPQQENIAA DNSAVHIHHS GDSTEMHHHF
     DTSIFTPSPA ISMPSPCTGV LSRQQARYLN HSNNSTVTSS PPSADDIFPS PHSSDPQSMS
     SWHSDALGTP GLFTPDLQSH DAQAWWPPMN ARVPQRQPSY QQVVASPPPQ QPIQNTTHQH
     DLANSQHDIL QGGLMIQMDP SAYDMTATAN SSFSSTTMAP TASSCQENHT YSHVPTAHAK
     YVDASSFATP QLHPQSRSPS LSPRADRSPK NGLAMHHSIT MKAQRRQPGR KISSNSMNVP
     KPVKGLNGSG SPKGAKSVTV SFVNFTLNDS QKILTGVAPS GSSKTKARRE QEARDRRRRI
     SEAALNAVRK AGGDVEALEA VMF