ID   WFD11_MOUSE             Reviewed;          82 AA.
AC   A2A5H7;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Protein WFDC11;
DE   Flags: Precursor;
GN   Name=Wfdc11;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- MISCELLANEOUS: Although this protein was isolated in a region
CC       containing several WAP proteins and was defined as a WAP protein, it
CC       does not contain a classical WAP domain.
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DR   EMBL; AL591478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS50797.1; -.
DR   RefSeq; NP_001155278.1; NM_001161806.1.
DR   RefSeq; XP_006500048.1; XM_006499985.3.
DR   AlphaFoldDB; A2A5H7; -.
DR   STRING; 10090.ENSMUSP00000104956; -.
DR   PhosphoSitePlus; A2A5H7; -.
DR   PaxDb; A2A5H7; -.
DR   PRIDE; A2A5H7; -.
DR   Antibodypedia; 70456; 28 antibodies from 5 providers.
DR   Ensembl; ENSMUST00000109332; ENSMUSP00000104956; ENSMUSG00000078940.
DR   Ensembl; ENSMUST00000167694; ENSMUSP00000125964; ENSMUSG00000078940.
DR   GeneID; 629761; -.
DR   KEGG; mmu:629761; -.
DR   UCSC; uc008nvp.1; mouse.
DR   CTD; 259239; -.
DR   MGI; MGI:3651686; Wfdc11.
DR   VEuPathDB; HostDB:ENSMUSG00000078940; -.
DR   eggNOG; ENOG502TE8U; Eukaryota.
DR   GeneTree; ENSGT00940000163115; -.
DR   HOGENOM; CLU_191873_0_0_1; -.
DR   InParanoid; A2A5H7; -.
DR   OMA; CGNICWE; -.
DR   OrthoDB; 1531872at2759; -.
DR   PhylomeDB; A2A5H7; -.
DR   TreeFam; TF338513; -.
DR   BioGRID-ORCS; 629761; 5 hits in 72 CRISPR screens.
DR   PRO; PR:A2A5H7; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; A2A5H7; protein.
DR   Bgee; ENSMUSG00000078940; Expressed in animal zygote and 7 other tissues.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:GO_Central.
DR   GO; GO:0019731; P:antibacterial humoral response; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   InterPro; IPR020310; WFDC11.
DR   PANTHER; PTHR19441:SF12; PTHR19441:SF12; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..82
FT                   /note="Protein WFDC11"
FT                   /id="PRO_0000415847"
SQ   SEQUENCE   82 AA;  9601 MW;  8326416288F7FEA7 CRC64;
     MKPSWFPCLV FLCMLLLSAL GGRKNKYYPG ELLLEECWGQ PKTNDCVKKC SRTFKCVYRN
     HTCCWTYCGN ICAENGKFFE RK