ID   WHIA_CLOAB              Reviewed;         317 AA.
AC   Q97LP1;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=CA_C0513;
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA   Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AE001437; AAK78493.1; -; Genomic_DNA.
DR   PIR; B96963; B96963.
DR   RefSeq; NP_347153.1; NC_003030.1.
DR   RefSeq; WP_010963835.1; NC_003030.1.
DR   AlphaFoldDB; Q97LP1; -.
DR   SMR; Q97LP1; -.
DR   STRING; 272562.CA_C0513; -.
DR   DNASU; 1116696; -.
DR   EnsemblBacteria; AAK78493; AAK78493; CA_C0513.
DR   GeneID; 44997022; -.
DR   KEGG; cac:CA_C0513; -.
DR   PATRIC; fig|272562.8.peg.712; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..317
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376455"
FT   DNA_BIND        281..314
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   317 AA;  36015 MW;  57BAE02409161935 CRC64;
     MSFSSKVKSE VCRYDDYSKG EAIAVLSAVM KASGTLALEG NRKISFKIIT ENPAIARLIF
     KLLKKYFDIH TEIMMKKSNS LKKNNVYVVS ITEDMGVREL LKTVGVMKNE DGIVTLSYDI
     PEFVVKDDES RKMYIRGAFL GGGSVSNPEK MYHLEFVTHN EDYASNLRDL INTYGLNSKV
     IQRKNSYVVY IKEGEQVVDL LNIIGAHSSL LELENIRIIK EMRNNINRLV NCETANLSKT
     VNASVRQIES IKLIEKQIGL SRLPENLREV AKLRLNYPDE SLKELGKMLE PPVGKSGVNH
     RLRKIEKIAE ELRKEGR