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WHIA_CLOBK
ID   WHIA_CLOBK              Reviewed;         315 AA.
AC   B1IFW1;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=CLD_1133;
OS   Clostridium botulinum (strain Okra / Type B1).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=498213;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Okra / Type B1;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000939; ACA44989.1; -; Genomic_DNA.
DR   RefSeq; WP_003357358.1; NC_010516.1.
DR   AlphaFoldDB; B1IFW1; -.
DR   SMR; B1IFW1; -.
DR   EnsemblBacteria; ACA44989; ACA44989; CLD_1133.
DR   GeneID; 5187629; -.
DR   KEGG; cbb:CLD_1133; -.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000008541; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..315
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376463"
FT   DNA_BIND        280..313
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   315 AA;  35924 MW;  CB67F89F7687EA5F CRC64;
     MSFSLKVKNE VCKHVEVNKQ EAIAELSAIM KVSGTLLFTN KQFNFKITTE NAAIARLVFK
     ILKEHFGIHT EIMIKKNNSL KKNNIYIILI SEEEGVKSLL KEVGIIKETI NVFSLDYNIP
     KSIIECDECR RAYIRGAFLG GGSISNPEKT YHLEFVTHNE EYAKDLSNLI NSYNLNSKVI
     KRKNSYIIYL KEGEQIVDLL NIIGAHASLL ELENVRIMKE MRNNVNRLVN CETANLSKTV
     NAAVRQVESI KFIEREIGLG RLPKNLRDVA ELRIKYPDES LRELGKMLNP PVGKSGVNHR
     LRRIEKIADE LKQGI
 
 
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