ID   WHIA_CLOPE              Reviewed;         316 AA.
AC   Q8XNH7;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=CPE0356;
OS   Clostridium perfringens (strain 13 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13 / Type A;
RX   PubMed=11792842; DOI=10.1073/pnas.022493799;
RA   Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA   Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT   "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT   eater.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; BA000016; BAB80062.1; -; Genomic_DNA.
DR   RefSeq; WP_011009761.1; NC_003366.1.
DR   AlphaFoldDB; Q8XNH7; -.
DR   SMR; Q8XNH7; -.
DR   STRING; 195102.gene:10489612; -.
DR   EnsemblBacteria; BAB80062; BAB80062; BAB80062.
DR   KEGG; cpe:CPE0356; -.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000000818; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..316
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376466"
FT   DNA_BIND        280..313
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   316 AA;  35796 MW;  8EB273A68C5F59B3 CRC64;
     MSFSAKVKGE ICRYIDISKE EALAQISAIM KVCGTLAFSG RQISFKMTTE NPASARLMFT
     ILKDYFDIHA KLMVKKSNSL KKNNIYMVVV TEEMGVKKLL EVTGILREID GIMSLDYHID
     ENLVDTEEKK KAYIRGAFIG GGSISNPEKT YHLEFVTHSQ EYAEDLGKLI NTFGLKAKVI
     QRKNSYIVYI KEGEQIVDLL NIIGAHTALL ELENIRIMKE MRNNVNRLVN CETANLSKTV
     NAAVRQVESI KLIEREIGLA RLPKNLREVA ELRLTYPEES LKELGEMLEP PVGKSGVNHR
     LRKIEKIAEE LRTGNF