ID   WHIA_CLOTE              Reviewed;         318 AA.
AC   Q890Y9;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=CTC_02493;
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88;
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H.,
RA   Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A.,
RA   Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AE015927; AAO36956.1; -; Genomic_DNA.
DR   RefSeq; WP_011100617.1; NC_004557.1.
DR   AlphaFoldDB; Q890Y9; -.
DR   SMR; Q890Y9; -.
DR   STRING; 212717.CTC_02493; -.
DR   EnsemblBacteria; AAO36956; AAO36956; CTC_02493.
DR   GeneID; 64180052; -.
DR   KEGG; ctc:CTC_02493; -.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..318
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376470"
FT   DNA_BIND        281..314
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   318 AA;  36123 MW;  F8244460BC7D3DF1 CRC64;
     MSFSSKVKNE VCRYDELEEK EAMALLSAIM RASGTLTFGR NKGIGFKIAT ENAAITRLVF
     KILKNILDIH TNIMIKKSNS FKKNNVYIIV INEEEGVKKL LEKTEVVKIE DIGFFINYNI
     SENLVYDDNT KKAYIRGAFL GGGSVSNPEK TYHLEFVTNN EMYANKLSEL INSYGLNSKV
     IQRKSNFIIY IKEGEQISDL LNIIGAHSSL LQLENIRIMK DMRNNINRIV NCETANLSKT
     VNAAVRQIES INLINKEIGL KRLPKNLRDM AEIRLKYPDV SLKELGEMLS PPVGKSGVNH
     RLRRIEKIAE ELSKEGNF