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WHIA_HALOH
ID   WHIA_HALOH              Reviewed;         313 AA.
AC   B8CYG6;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=Hore_15860;
OS   Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562).
OC   Bacteria; Firmicutes; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC   Halothermothrix.
OX   NCBI_TaxID=373903;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H 168 / OCM 544 / DSM 9562;
RX   PubMed=19145256; DOI=10.1371/journal.pone.0004192;
RA   Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H.,
RA   Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.;
RT   "Genome analysis of the anaerobic thermohalophilic bacterium
RT   Halothermothrix orenii.";
RL   PLoS ONE 4:E4192-E4192(2009).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP001098; ACL70335.1; -; Genomic_DNA.
DR   RefSeq; WP_012636518.1; NC_011899.1.
DR   AlphaFoldDB; B8CYG6; -.
DR   SMR; B8CYG6; -.
DR   STRING; 373903.Hore_15860; -.
DR   EnsemblBacteria; ACL70335; ACL70335; Hore_15860.
DR   KEGG; hor:Hore_15860; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000000719; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376489"
FT   DNA_BIND        278..311
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   313 AA;  36092 MW;  1097A47361CA3E01 CRC64;
     MSFTDQVKHE VSRLESNNKM CQLAELSALI MMNGSIQIIN KNLAVKVRLY HGDLARKVYK
     LIKERFELNI EIMVRRRNHF STYQNIYDLF LPPQPGIEVF LKKVGVLDED HNLLFRIKKE
     LVTSKSCQKS YVRGAFLGGG SVNNPRGEYH LEFRCEHESF AEDLLMLLKR FGLEGHLTEH
     RKKYVVYFKS FSEVATILNI IGAHKALLKL EDNKVLKEVK NGVNRRVNCE TANLDKTVKA
     AMLQLEDIEL IEKTRGLETL SNSLQEIAII RKKYPYASLK ELGKLLDPPL SKSGVNHRLR
     RIKSIANEIR GER
 
 
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