ID   WHIA_HELMI              Reviewed;         319 AA.
AC   B0TGK8;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=Helmi_06440;
GN   ORFNames=HM1_1308;
OS   Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Heliobacteriaceae;
OC   Heliomicrobium.
OX   NCBI_TaxID=498761;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51547 / Ice1;
RX   PubMed=18441057; DOI=10.1128/jb.00299-08;
RA   Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA   Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA   Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA   Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT   "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT   of the Firmicutes containing the simplest photosynthetic apparatus.";
RL   J. Bacteriol. 190:4687-4696(2008).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000930; ABZ83269.1; -; Genomic_DNA.
DR   RefSeq; WP_012281803.1; NC_010337.2.
DR   AlphaFoldDB; B0TGK8; -.
DR   SMR; B0TGK8; -.
DR   STRING; 498761.HM1_1308; -.
DR   PRIDE; B0TGK8; -.
DR   EnsemblBacteria; ABZ83269; ABZ83269; HM1_1308.
DR   KEGG; hmo:HM1_1308; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000008550; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..319
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376490"
FT   DNA_BIND        278..311
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   319 AA;  35838 MW;  A6A7A7DD8E5312B0 CRC64;
     MSFSVETKEE LARIQPRRRC CQLAELAALF RMDGSLQISG EQGLSLTVST ESASSARKIF
     RLIKAVFGVQ TQILVRRKRR LKKSNVYVIS LPARIGGRDV LQEMGITDSQ GGFSFEPPSE
     LLKRQCCRRA YLRGAFLGGG SVNSPEGTYH LEIITNDETH ARILSELLHR FGLTAKVSQR
     KGWFIVYLKE SEQIVEMLSI IGAHSALLNF ENVRIVKGMR NQVNRLVNCE TANLNKTVDA
     ALRQTEMIRF VQNRIGFANL PSQLREVAEL RLQYPDASLK ELGQMLNPPV GKSGVNHRLR
     RLESLAEAFS RQGGVPRED