ID   WHIA_LACCB              Reviewed;         315 AA.
AC   B3WCR0;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=LCABL_10750;
OS   Lacticaseibacillus casei (strain BL23) (Lactobacillus casei).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=543734;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BL23;
RA   Maze A., Boel G., Bourand A., Loux V., Gibrat J.F., Zuniga M., Hartke A.,
RA   Deutscher J.;
RT   "Lactobacillus casei BL23 complete genome sequence.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; FM177140; CAQ66161.1; -; Genomic_DNA.
DR   RefSeq; WP_012491296.1; NC_010999.1.
DR   AlphaFoldDB; B3WCR0; -.
DR   SMR; B3WCR0; -.
DR   KEGG; lcb:LCABL_10750; -.
DR   HOGENOM; CLU_053282_1_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..315
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376496"
FT   DNA_BIND        277..311
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   315 AA;  35868 MW;  44A548E9791B9CAC CRC64;
     MASFASLVKK ELTQLEVHPE HAKAELSALI RMNGSLTLMA HRFVLNIQTE NPAIARRIYS
     LIRQVYHHEA NLVVHRKMKL KKNYQYIVRL TEGVNDILSD LSILDPDTMA ISTTVPTSVL
     KEPQRMRSYL RGAFLASGSV NNPETSRYHL EIYSLYDNHN AGILKMMNHF HLNARTVERR
     SGYIVYLKEA EKIADFLQVI GATNAMLKFE DVRIMRDMRN SVNRLVNCEN ANMNKTIDAA
     QKQIENINYL KNHVGLDNLP AKLREIAVLR LAHPDVSLQE LGAMMPSGQI SKSGVNHRLR
     KLNQIAEGYQ QPEDA