WHIA_LACDA
ID WHIA_LACDA Reviewed; 310 AA.
AC Q1GB32;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=Ldb0623;
OS Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081
OS / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM
OS 00102 / Lb 14).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=390333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB
RC 11778 / NCTC 12712 / WDCM 00102 / Lb 14;
RX PubMed=16754859; DOI=10.1073/pnas.0603024103;
RA van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P.,
RA Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R.,
RA Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P.,
RA Weissenbach J., Ehrlich S.D., Maguin E.;
RT "The complete genome sequence of Lactobacillus bulgaricus reveals extensive
RT and ongoing reductive evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; CR954253; CAI97453.1; -; Genomic_DNA.
DR RefSeq; WP_011543731.1; NZ_JQAV01000001.1.
DR AlphaFoldDB; Q1GB32; -.
DR SMR; Q1GB32; -.
DR STRING; 390333.Ldb0623; -.
DR EnsemblBacteria; CAI97453; CAI97453; Ldb0623.
DR KEGG; ldb:Ldb0623; -.
DR PATRIC; fig|390333.13.peg.175; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_1_0_9; -.
DR OMA; CDAEAAW; -.
DR BioCyc; LDEL390333:LDB_RS02695-MON; -.
DR Proteomes; UP000001259; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..310
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376497"
FT DNA_BIND 277..310
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 310 AA; 35039 MW; E7B7A526D7EBE2BB CRC64;
MASYASEVKK ELTSIEVHPE HAKAELAAFL RMNAVLSRHD GQMSLDIVTE NPAIARRIFS
LIKTAYGFDP QLIVTRKMKL KKNHQYLVRV AQMVSEIMAD LEIYSPKKGF ITGVPDKIKY
SEQRSMSYLR GGFLASGSVN NPETSRYHLE IYCTYANHSQ DLQEIMNKYF DLNAKVTARR
SGSIVYLKEA EKIGDFLHVV GAVNAMLAFE DLRIMRDMRN SVNRLVNCDT ANLRKTAGAA
AKQVEDIELI DKKQGLEPLP EKLASLARFR LQHPELSLKE LAEQVPDGPI SKSGVNHRLK
KLHEIAENLR