ID   WHIA_LACH4              Reviewed;         311 AA.
AC   A8YUD8;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=lhv_0734;
OS   Lactobacillus helveticus (strain DPC 4571).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=405566;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DPC 4571;
RX   PubMed=17993529; DOI=10.1128/jb.01295-07;
RA   Callanan M., Kaleta P., O'Callaghan J., O'Sullivan O., Jordan K.,
RA   McAuliffe O., Sangrador-Vegas A., Slattery L., Fitzgerald G.F.,
RA   Beresford T., Ross R.P.;
RT   "Genome sequence of Lactobacillus helveticus: an organism distinguished by
RT   selective gene loss and IS element expansion.";
RL   J. Bacteriol. 190:727-735(2008).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000517; ABX26876.1; -; Genomic_DNA.
DR   RefSeq; WP_012211624.1; NC_010080.1.
DR   AlphaFoldDB; A8YUD8; -.
DR   SMR; A8YUD8; -.
DR   STRING; 405566.lhv_0734; -.
DR   EnsemblBacteria; ABX26876; ABX26876; lhv_0734.
DR   KEGG; lhe:lhv_0734; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_1_0_9; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000000790; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..311
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376501"
FT   DNA_BIND        277..311
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   311 AA;  35572 MW;  7848EDC902FE420A CRC64;
     MASYASEVKK ELTSLEVHPE HAKAELAAFL RMNGVLNLHD HQFSLDITTE NPAIARRIFK
     LIKVAYGIEP LLIVSRKMKL KKNNQYLVRL NRDVQKILEN LNIWDPAKGL VTRIPQRIMK
     SSEGAMSYLR GAFLAGGSVN NPETSRYHLE IYSTYEDHNE DLAKLMNEYF YLNAKMTKRR
     RGYIVYLKEA AKIGDFLHVV GALNAMLNFE DLRIMRDMRN SVNRLVNCDT ANMKKTASAS
     AKQVEDIQLI QKEKGIDSLP EKLQILARFR LAHPELTLKE VADQIPDGPI SKSGVNHRFK
     KLHELAETLK E