ID   WHIA_LIGS1              Reviewed;         315 AA.
AC   Q1WT80;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=LSL_1169;
OS   Ligilactobacillus salivarius (strain UCC118) (Lactobacillus salivarius).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=362948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCC118;
RX   PubMed=16617113; DOI=10.1073/pnas.0511060103;
RA   Claesson M.J., Li Y., Leahy S., Canchaya C., van Pijkeren J.P.,
RA   Cerdeno-Tarraga A.M., Parkhill J., Flynn S., O'Sullivan G.C., Collins J.K.,
RA   Higgins D., Shanahan F., Fitzgerald G.F., van Sinderen D., O'Toole P.W.;
RT   "Multireplicon genome architecture of Lactobacillus salivarius.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:6718-6723(2006).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000233; ABD99977.1; -; Genomic_DNA.
DR   RefSeq; WP_003700622.1; NC_007929.1.
DR   RefSeq; YP_536060.1; NC_007929.1.
DR   AlphaFoldDB; Q1WT80; -.
DR   SMR; Q1WT80; -.
DR   STRING; 362948.LSL_1169; -.
DR   EnsemblBacteria; ABD99977; ABD99977; LSL_1169.
DR   GeneID; 57059597; -.
DR   KEGG; lsl:LSL_1169; -.
DR   PATRIC; fig|362948.14.peg.1243; -.
DR   HOGENOM; CLU_053282_1_0_9; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000006559; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..315
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376507"
FT   DNA_BIND        274..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   315 AA;  35947 MW;  4EA0BFEB3A2E36C7 CRC64;
     MSYASDVKKE LTMLEVHFGN AKAELMALIR MNGSLSIVNK QFVLSVQTEN PAIARRIYRL
     LKQFYDIESE LIVRRKMKLK KNNFYIVRLK TGTNEILKDL DILDNFQIKE TVPLEFLDDD
     AKVRSYLRGA FLATGSVNNP ETSRYHLEIY SLYEDHNDTI CEMMNRYGLN ARKTERRSGY
     ITYLKEAEKI ADFLSLIGAT NAMLKFEDIR IVRDMRNSVN RIVNCETANL NKIADASKKQ
     IDNIKLIDAK VGIDKLPQKL QEVAIARLGH PEESLKNLGE LIPGGPISKS GINHRLRKLN
     EIAEKIRAGE SIAVL