ID   WHIA_LIMRD              Reviewed;         313 AA.
AC   A5VII3;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=Lreu_0388;
OS   Limosilactobacillus reuteri (strain DSM 20016) (Lactobacillus reuteri).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=557436;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20016;
RX   PubMed=21379339; DOI=10.1371/journal.pgen.1001314;
RA   Frese S.A., Benson A.K., Tannock G.W., Loach D.M., Kim J., Zhang M.,
RA   Oh P.L., Heng N.C., Patil P.B., Juge N., Mackenzie D.A., Pearson B.M.,
RA   Lapidus A., Dalin E., Tice H., Goltsman E., Land M., Hauser L., Ivanova N.,
RA   Kyrpides N.C., Walter J.;
RT   "The evolution of host specialization in the vertebrate gut symbiont
RT   Lactobacillus reuteri.";
RL   PLoS Genet. 7:E1001314-E1001314(2011).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; CP000705; ABQ82657.1; -; Genomic_DNA.
DR   RefSeq; WP_003667466.1; NZ_AZDD01000014.1.
DR   AlphaFoldDB; A5VII3; -.
DR   SMR; A5VII3; -.
DR   STRING; 557436.Lreu_0388; -.
DR   EnsemblBacteria; ABQ82657; ABQ82657; Lreu_0388.
DR   GeneID; 66470495; -.
DR   KEGG; lre:Lreu_0388; -.
DR   PATRIC; fig|557436.17.peg.428; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000001991; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376504"
FT   DNA_BIND        274..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   313 AA;  35727 MW;  A19639E53B4B0381 CRC64;
     MSYASEVKKE LTGITVHRDN AKAELMALIR MNGSIGIADH QLVLNVQTEN PAIARRIYSL
     LKQFYGVESE IVVRRKMKLK KNNQYIVRLR YHAQHVLDDL GILQNYQIKE QVPVELLKDE
     WMVRSYLRGA FLAGGSVNNP ETSRYHLEIY SLYEEHNEII AQMMNKFGLN AQTTARRSGF
     IVYLKEAEKI ANFMSLIGAT NSMLQFENVR IVRDMRNSVN RLVNCENANL NKIANASTRQ
     IENIEFIDSR VGLSSLPDKL REIAETRLAH QEVSLKELGE LVPGGPISKS GVNHRLRKLN
     AYADELRASE VKQ