ID   WHIA_MACCJ              Reviewed;         316 AA.
AC   B9EAG4;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MCCL_0518;
OS   Macrococcus caseolyticus (strain JCSC5402).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Macrococcus.
OX   NCBI_TaxID=458233;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC5402;
RX   PubMed=19074389; DOI=10.1128/jb.01058-08;
RA   Baba T., Kuwahara-Arai K., Uchiyama I., Takeuchi F., Ito T., Hiramatsu K.;
RT   "Complete genome sequence of Macrococcus caseolyticus strain JCSCS5402,
RT   reflecting the ancestral genome of the human-pathogenic staphylococci.";
RL   J. Bacteriol. 191:1180-1190(2009).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AP009484; BAH17225.1; -; Genomic_DNA.
DR   RefSeq; WP_012656426.1; NC_011999.1.
DR   AlphaFoldDB; B9EAG4; -.
DR   SMR; B9EAG4; -.
DR   STRING; 458233.MCCL_0518; -.
DR   PRIDE; B9EAG4; -.
DR   EnsemblBacteria; BAH17225; BAH17225; MCCL_0518.
DR   GeneID; 61129682; -.
DR   KEGG; mcl:MCCL_0518; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_9; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000001383; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..316
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_1000184856"
FT   DNA_BIND        274..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   316 AA;  36200 MW;  37B13917F1B01BC1 CRC64;
     MSFASEMKNE LTRIETDLCC SKAELAALIR MNGNLNIQNM QWVINVQSEN AAIARRVYSL
     TKKIFGVDIE LLVRKKMKLK KNNVYICRIK MKTKEILDEL SILQDGQFVQ HIDQSLIKEE
     CCKRSYLRGA FLAGGSVNNP ETSSYHLEIF SLYESHSEGL TEMMNGYGLN AKTLERKKGY
     ISYLKEAEKI SDFLSIIGGY QALLKFEDVR IVRDMRNSVN RLVNCETANL NKTIGAAMRQ
     VENIRLIDEE IGIDELPERL REIARLRVQH QDISLKELGE MVSTGVISKS GVNHRLRKID
     EIAEKLRNGE HIELKK