WHIA_MYCA9
ID WHIA_MYCA9 Reviewed; 327 AA.
AC B1MC89;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MAB_2781c;
OS Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM
OS 13569 / NCTC 13031 / TMC 1543) (Mycobacterium abscessus).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacteroides; Mycobacteroides abscessus.
OX NCBI_TaxID=561007;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC
RC 1543;
RX PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA Gaillard J.L.;
RT "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT Mycobacterium abscessus.";
RL PLoS ONE 4:E5660-E5660(2009).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAM62860.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR EMBL; CU458896; CAM62860.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; B1MC89; -.
DR SMR; B1MC89; -.
DR EnsemblBacteria; CAM62860; CAM62860; MAB_2781c.
DR GeneID; 66973145; -.
DR KEGG; mab:MAB_2781c; -.
DR OMA; CDAEAAW; -.
DR Proteomes; UP000007137; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding.
FT CHAIN 1..327
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376521"
FT DNA_BIND 275..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
FT REGION 307..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 35097 MW; 7FFDC82C449FE844 CRC64;
MAMTAEVKDE LSRLVVTQVS SRRAEVASLL RFAGGLHIVS GRVVVEAEVD QGSIARRLRK
DIFDLYGYNA VVHVLSAGGI RKTTRYVVRV AKDGEALARQ TGLLDLRGRP VRGLPAQVVG
GSVADAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VSAKAREVRG
SDRVVVRDGE AIGALLTRMG AQDTRLTWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAAARVERAL EILGDTVPDH LAAAGKLRVE HRQASLEELG RLADPVMTKD AVAGRIRRLL
SMADRKAKTE GIPDTESAVT PELLEEA