ID   WHIA_MYCBP              Reviewed;         327 AA.
AC   A1KIL2;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-MAY-2022, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=BCG_1484;
OS   Mycobacterium bovis (strain BCG / Pasteur 1173P2).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=410289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Pasteur 1173P2;
RX   PubMed=17372194; DOI=10.1073/pnas.0700869104;
RA   Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P.,
RA   Dos Santos S., Duthoy S., Lacroix C., Garcia-Pelayo C., Inwald J.K.,
RA   Golby P., Garcia J.N., Hewinson R.G., Behr M.A., Quail M.A., Churcher C.,
RA   Barrell B.G., Parkhill J., Cole S.T.;
RT   "Genome plasticity of BCG and impact on vaccine efficacy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:5596-5601(2007).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAL71471.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR   EMBL; AM408590; CAL71471.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_003901156.1; NC_008769.1.
DR   AlphaFoldDB; A1KIL2; -.
DR   SMR; A1KIL2; -.
DR   GeneID; 45425401; -.
DR   KEGG; mbb:BCG_1484; -.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000001472; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..327
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376524"
FT   DNA_BIND        275..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   327 AA;  35135 MW;  DA43F3E276081D36 CRC64;
     MAMTTDVKDE LSRLVVKSVS ARRAEVTSLL RFAGGLHIVG GRVVVEAELD LGSIARRLRK
     EIFELYGYTA VVHVLSASGI RKSTRYVLRV ANDGEALARQ TGLLDMRGRP VRGLPAQVVG
     GSIDDAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VGAKAREVRG
     ADRVVVRDGE AIGALLTRMG AQDTRLVWEE RRLRREVRAT ANRLANFDDA NLRRSARAAV
     AAAARVERAL EILGDTVPEH LASAGKLRVE HRQASLEELG RLADPPMTKD AVAGRIRRLL
     SMADRKAKVD GIPDTESVVT PDLLEDA