ID   WHIA_MYCBT              Reviewed;         325 AA.
AC   C1AN68;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=JTY_1459;
OS   Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=561275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCG / Tokyo 172 / ATCC 35737 / TMC 1019;
RX   PubMed=19200449; DOI=10.1016/j.vaccine.2009.01.034;
RA   Seki M., Honda I., Fujita I., Yano I., Yamamoto S., Koyama A.;
RT   "Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-
RT   Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.";
RL   Vaccine 27:1710-1716(2009).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AP010918; BAH25747.1; -; Genomic_DNA.
DR   RefSeq; WP_003901156.1; NZ_CP014566.1.
DR   AlphaFoldDB; C1AN68; -.
DR   SMR; C1AN68; -.
DR   GeneID; 45425401; -.
DR   KEGG; mbt:JTY_1459; -.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   OMA; CDAEAAW; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..325
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_1000184857"
FT   DNA_BIND        273..306
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   325 AA;  34933 MW;  E3EB4C1804267360 CRC64;
     MTTDVKDELS RLVVKSVSAR RAEVTSLLRF AGGLHIVGGR VVVEAELDLG SIARRLRKEI
     FELYGYTAVV HVLSASGIRK STRYVLRVAN DGEALARQTG LLDMRGRPVR GLPAQVVGGS
     IDDAEAAWRG AFLAHGSLTE PGRSSALEVS CPGPEAALAL VGAARRLGVG AKAREVRGAD
     RVVVRDGEAI GALLTRMGAQ DTRLVWEERR LRREVRATAN RLANFDDANL RRSARAAVAA
     AARVERALEI LGDTVPEHLA SAGKLRVEHR QASLEELGRL ADPPMTKDAV AGRIRRLLSM
     ADRKAKVDGI PDTESVVTPD LLEDA