WHIA_MYCGE
ID WHIA_MYCGE Reviewed; 280 AA.
AC P47349; Q49293;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MG103;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 86-208.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; L43967; AAC71321.1; -; Genomic_DNA.
DR EMBL; U02170; AAD12452.1; -; Genomic_DNA.
DR PIR; D64211; D64211.
DR RefSeq; WP_010869332.1; NC_000908.2.
DR AlphaFoldDB; P47349; -.
DR SMR; P47349; -.
DR STRING; 243273.MG_103; -.
DR EnsemblBacteria; AAC71321; AAC71321; MG_103.
DR KEGG; mge:MG_103; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_993285_0_0_14; -.
DR OMA; IWNENNT; -.
DR OrthoDB; 1634356at2; -.
DR BioCyc; MGEN243273:G1GJ2-115-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IBA:GO_Central.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..280
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000210415"
FT DNA_BIND 247..279
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
FT CONFLICT 86
FT /note="L -> F (in Ref. 2; AAD12452)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 280 AA; 32864 MW; 022BC4D71D735A2D CRC64;
MTFSTQIKAE LVQNKLIDKH WNVFLAGFFQ NNLKLLYNRN WSFKVQSEAL KEQFVQNLKF
DFKTKASKKY FLFEFNADIN VINTLLKLDV TTSELVVKQV YLIAAFLSGG SVSDLINSNN
FHLQISSNNE FQIQQLLKLF SFFKKTVKQN QLVVYLKSYE KICNFLKLIQ AFDGYLAFEN
KQLEKSFTLN QLRKSNLEVA NLMKTIRSNN QTNQLQLKSF IKSSSFAKRP LNFQRYCLIK
SDHPDWSLEQ IANFFFTKYN IKISRSGIQH FSVNLKKLCQ
