ID   WHIA_MYCLB              Reviewed;         327 AA.
AC   B8ZUN8;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-MAY-2022, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MLBr00565;
OS   Mycobacterium leprae (strain Br4923).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=561304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Br4923;
RX   PubMed=19881526; DOI=10.1038/ng.477;
RA   Monot M., Honore N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A.,
RA   Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A., Mays S., Watson C.,
RA   Lockwood D., Khamispour A., Dowlati Y., Jianping S., Rea T.H.,
RA   Vera-Cabrera L., Stefani M.M., Banu S., Macdonald M., Sapkota B.R.,
RA   Spencer J.S., Thomas J., Harshman K., Singh P., Busso P., Gattiker A.,
RA   Rougemont J., Brennan P.J., Cole S.T.;
RT   "Comparative genomic and phylogeographic analysis of Mycobacterium
RT   leprae.";
RL   Nat. Genet. 41:1282-1289(2009).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAR70658.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR   EMBL; FM211192; CAR70658.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010907803.1; NC_011896.1.
DR   AlphaFoldDB; B8ZUN8; -.
DR   SMR; B8ZUN8; -.
DR   EnsemblBacteria; CAR70658; CAR70658; MLBr00565.
DR   KEGG; mlb:MLBr00565; -.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000006900; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..327
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376527"
FT   DNA_BIND        275..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   327 AA;  35331 MW;  15A9594E29F95F30 CRC64;
     MAMTIEVKDE LSRLAVKSIS ARRAEVTSLL RFAGGLHIVG GRVVIEAEVD LENIARRLRK
     DIFDLYGYNA VVHVLSASGI RKSVRYVLRV ANDGEALARQ TGLLDMRGRP VRGLPAQVVG
     GSLIDAEAVW RGAFLAHGSL TEPGRSSALE VSCPGLEAAL ALVGAARKLG VNAKAREVRG
     ADRVVVRDGE AIGVLLTRMG AQDTRLVWEE RRMRREVRAT ANRLANFDDA NLRRSARAAI
     AAAARAERAL EILGDTVPDH LASAGKLRVE YRQASLEELG RLADPPMTKD AVAGRIRRLL
     SMADRKAKVE GIPDTESAVT PDLLEDA