WHIA_MYCPA
ID WHIA_MYCPA Reviewed; 327 AA.
AC Q741E2;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MAP_1149;
OS Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS (Mycobacterium paratuberculosis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=262316;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-968 / K-10;
RX PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA Kanjilal S., Kapur V.;
RT "The complete genome sequence of Mycobacterium avium subspecies
RT paratuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAS03466.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR EMBL; AE016958; AAS03466.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_003872529.1; NC_002944.2.
DR AlphaFoldDB; Q741E2; -.
DR SMR; Q741E2; -.
DR STRING; 262316.MAP_1149; -.
DR EnsemblBacteria; AAS03466; AAS03466; MAP_1149.
DR GeneID; 66694600; -.
DR KEGG; mpa:MAP_1149; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_0_0_11; -.
DR OMA; CDAEAAW; -.
DR Proteomes; UP000000580; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..327
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376529"
FT DNA_BIND 275..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 327 AA; 35134 MW; 71B173A2E9339FAF CRC64;
MAMTTEVKDE LSRLVVKSVS ARRAEVTSLL RFAGGLHIVG GRVVVEAEVD LGNVARRLRK
DIFELYGYNA VVHVLSASGI RKSTRYVLRV ANDGEALARQ TGLLDNRGRP VRGLPAQVVG
GSIADAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VSAKAREVRG
ADRVVVRDGE AIGALLTRMG AQDTRLIWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAAARVERAL EILGDTVPDH LASAGKLRVE HRQASLEELG RLADPPMTKD AVAGRIRRLL
SMADRKAKIE GIPDTESAVT PDLLEDA