WHIA_MYCSK
ID WHIA_MYCSK Reviewed; 327 AA.
AC A1UFN5;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=Mkms_2445;
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; unclassified Mycobacterium.
OX NCBI_TaxID=189918;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABL91643.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR EMBL; CP000518; ABL91643.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_011559795.1; NC_008705.1.
DR AlphaFoldDB; A1UFN5; -.
DR SMR; A1UFN5; -.
DR STRING; 189918.Mkms_2445; -.
DR EnsemblBacteria; ABL91643; ABL91643; Mkms_2445.
DR KEGG; mkm:Mkms_2445; -.
DR HOGENOM; CLU_053282_0_0_11; -.
DR OMA; CDAEAAW; -.
DR OrthoDB; 1634356at2; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding.
FT CHAIN 1..327
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376532"
FT DNA_BIND 275..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
FT REGION 304..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 35097 MW; 6454D47C546BD9C6 CRC64;
MAMTAEVKDE LSRLVVNSVS ARRAEVASLL RFAGGLHIVS GRVVVEAEVD LGIIARRLRK
DIYDLYGYNA VVHMLSASGI RKGTRYVVRV AKDGEALARQ TGLLDLRGRP VRGLPAQVVG
GSVADAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VSAKAREVRG
SDRVVVRDGE AIGALLTRMG AQDTRLTWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAAARVERAL EILGDTVPDH LASAGKLRVE HRQASLEELG RLADPPMTKD AVAGRIRRLL
SMADRKAKQD GIPDTESAVT PDLLEDA