ID   WHIA_MYCTO              Reviewed;         327 AA.
AC   P9WF44; L0T6T7; P71692; Q7D8G9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   07-JAN-2015, sequence version 2.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MT1466;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AE000516; AAK45731.1; -; Genomic_DNA.
DR   PIR; D70903; D70903.
DR   AlphaFoldDB; P9WF44; -.
DR   SMR; P9WF44; -.
DR   EnsemblBacteria; AAK45731; AAK45731; MT1466.
DR   KEGG; mtc:MT1466; -.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..327
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000428603"
FT   DNA_BIND        275..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   327 AA;  35135 MW;  DA43F3E276081D36 CRC64;
     MAMTTDVKDE LSRLVVKSVS ARRAEVTSLL RFAGGLHIVG GRVVVEAELD LGSIARRLRK
     EIFELYGYTA VVHVLSASGI RKSTRYVLRV ANDGEALARQ TGLLDMRGRP VRGLPAQVVG
     GSIDDAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VGAKAREVRG
     ADRVVVRDGE AIGALLTRMG AQDTRLVWEE RRLRREVRAT ANRLANFDDA NLRRSARAAV
     AAAARVERAL EILGDTVPEH LASAGKLRVE HRQASLEELG RLADPPMTKD AVAGRIRRLL
     SMADRKAKVD GIPDTESVVT PDLLEDA