ID   WHIA_MYCUA              Reviewed;         327 AA.
AC   A0PPM4;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-MAY-2022, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=MUL_1817;
OS   Mycobacterium ulcerans (strain Agy99).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=362242;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Agy99;
RX   PubMed=17210928; DOI=10.1101/gr.5942807;
RA   Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA   Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA   Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.,
RA   Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.;
RT   "Reductive evolution and niche adaptation inferred from the genome of
RT   Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL   Genome Res. 17:192-200(2007).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABL04293.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR   EMBL; CP000325; ABL04293.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A0PPM4; -.
DR   SMR; A0PPM4; -.
DR   STRING; 362242.MUL_1817; -.
DR   PRIDE; A0PPM4; -.
DR   EnsemblBacteria; ABL04293; ABL04293; MUL_1817.
DR   KEGG; mul:MUL_1817; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   OMA; CDAEAAW; -.
DR   Proteomes; UP000000765; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding.
FT   CHAIN           1..327
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376536"
FT   DNA_BIND        275..308
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   327 AA;  35128 MW;  132DDFA7F5DE186A CRC64;
     MAMTTEVKDE LSRLVVKSVS ARRAEVTSLL RFAGGLHIVA GRVVVEAEVD LGSIARRLRK
     DIFDLYGYSA VVHVLSASGI RKNTRYVLRV ANDGEALARQ TGLFDMRGRP VRGLPAQVVG
     GSIGDAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG VGAKAREVRG
     ADRVVVRDGE AIGALLTRMG AQDTRLVWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
     AAAARVERAL EILGDTVPDH LASAGKLRVE HRQVSLEELG RLADPPMTKD AVAGRIRRLL
     SMADRKAKVE GIPDTESAVT PDLLEDA