WHIA_NOCFA
ID WHIA_NOCFA Reviewed; 327 AA.
AC Q5YTQ2;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=NFA_35910;
OS Nocardia farcinica (strain IFM 10152).
OC Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX NCBI_TaxID=247156;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFM 10152;
RX PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA Shiba T., Hattori M.;
RT "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD58439.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000250|UniProtKB:P9WF45};
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DR EMBL; AP006618; BAD58439.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; Q5YTQ2; -.
DR SMR; Q5YTQ2; -.
DR STRING; 247156.NFA_35910; -.
DR EnsemblBacteria; BAD58439; BAD58439; NFA_35910.
DR KEGG; nfa:NFA_35910; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_0_0_11; -.
DR OMA; CDAEAAW; -.
DR Proteomes; UP000006820; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..327
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376539"
FT DNA_BIND 275..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 327 AA; 35142 MW; 67F505503E277263 CRC64;
MAMTAEVKDE LSRLTVSQVS SRKAELSALL RFAGGLHIVG GRVIVEAEVD MGSIARRLRR
EIFELYGYGS DVHVLGAGGL RKTSRYVVRV SKEGEALARQ TGLLDVRGRP VRGLPAQVVG
GSIADAEAAW RGAFLAHGSL TEPGRSSALE VSCPGPEAAL ALVGAARRLG ITAKAREVRG
TDRVVVRDGE AIGALLTRMG AQDTRLTWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAAARVERAL EILGEDVPDH LAAAGKLRVQ HRQASLEELG QLADPPMTKD AVAGRIRRLL
SMADRRAREL GIPDTESAVT AELLDEA