WHIA_PEDPA
ID WHIA_PEDPA Reviewed; 309 AA.
AC Q03GX4;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=PEPE_0452;
OS Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 /
OS 183-1w).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus.
OX NCBI_TaxID=278197;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w;
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; CP000422; ABJ67548.1; -; Genomic_DNA.
DR RefSeq; WP_002834077.1; NC_008525.1.
DR AlphaFoldDB; Q03GX4; -.
DR SMR; Q03GX4; -.
DR STRING; 278197.PEPE_0452; -.
DR EnsemblBacteria; ABJ67548; ABJ67548; PEPE_0452.
DR GeneID; 33062375; -.
DR KEGG; ppe:PEPE_0452; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_0_0_9; -.
DR OMA; CDAEAAW; -.
DR OrthoDB; 1634356at2; -.
DR Proteomes; UP000000773; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..309
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376543"
FT DNA_BIND 275..309
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 309 AA; 35486 MW; AB87E3C31FFEFA7D CRC64;
MSYASEVKKE LTSLEVHEKN AKAELMALIR MNGAIGINNR QLTLNTQTEN PAIARRIYSL
LKEFYHLEAE LSVRRKMKLK KNNLYIVRLR TGVKELLNDL SILKDDFQIN EKVPEGLLTE
ESELRSYLRG AFLASGSVNN PETSRYHLEI YSLYESHNQM IADWINKYNL NARTTERRSG
YIVYLKEAEH IADFLQLIGA TNSMLKFEDV RIMRDMRNSV NRLVNCETAN LNKVANASMK
QINNIQFIDE TVGLGELPPK LREVAEARLI HREVSLKELG ELVPGGPISK SGINHRLRKI
NQYAEKLRA