WHIA_STAA1
ID WHIA_STAA1 Reviewed; 314 AA.
AC A7WZR7;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=SAHV_0764;
OS Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=418127;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu3 / ATCC 700698;
RX PubMed=17954695; DOI=10.1128/aac.00534-07;
RA Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT "Mutated response regulator graR is responsible for phenotypic conversion
RT of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT resistance to vancomycin-intermediate resistance.";
RL Antimicrob. Agents Chemother. 52:45-53(2008).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; AP009324; BAF77647.1; -; Genomic_DNA.
DR RefSeq; WP_000006551.1; NZ_CTYB01000039.1.
DR AlphaFoldDB; A7WZR7; -.
DR SMR; A7WZR7; -.
DR KEGG; saw:SAHV_0764; -.
DR HOGENOM; CLU_053282_0_0_9; -.
DR OMA; CDAEAAW; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding.
FT CHAIN 1..314
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376557"
FT DNA_BIND 274..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 314 AA; 35868 MW; 5220A1A82EBB6074 CRC64;
MSFASEMKNE LTRIDVDEMN AKAELSALIR MNGALSLSNQ QFVINVQTEN ATTARRIYSL
IKRVFNVEVE ILVRKKMKLK KNNIYICRTK MKAKEILDEL GILKDGIFTH EIDHSMIQDD
EMRRSYLRGA FLAGGSVNNP ETSSYHLEIF SQNESHAEGL TKLMNSYELN AKHLERKKGS
ITYLKEAEKI SDFLSLIGGY QALLKFEDVR IVRDMRNSVN RLVNCETANL NKTVSAAMKQ
VESIKLIDKE IGIENLPDRL REIARIRVEH QEISLKELGE MVSTGPISKS GVNHRLRKLN
DLADKIRNGE QIEL