WHIA_STRAW
ID WHIA_STRAW Reviewed; 329 AA.
AC Q829W5;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=SAV_6294;
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces.
OX NCBI_TaxID=227882;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC 8165 / MA-4680;
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC 8165 / MA-4680;
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; BA000030; BAC74005.1; -; Genomic_DNA.
DR RefSeq; WP_010987695.1; NZ_JZJK01000089.1.
DR AlphaFoldDB; Q829W5; -.
DR SMR; Q829W5; -.
DR STRING; 227882.SAV_6294; -.
DR EnsemblBacteria; BAC74005; BAC74005; SAVERM_6294.
DR KEGG; sma:SAVERM_6294; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_0_0_11; -.
DR OMA; CDAEAAW; -.
DR OrthoDB; 1634356at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..329
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376599"
FT DNA_BIND 275..308
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 329 AA; 35079 MW; BC6EC7D651CE27D5 CRC64;
MAMTAAVKDE ISRLPVTRTC CRKAEVSAIL RFAGGLHLVS GRIVIEAELD TAMAARRLKR
DILEIFGHSS ELIVMAPGGL RRGSRYVVRV VAGGDQLARQ TGLVDGRGRP IRGLPPQVVS
GATCDAEAAW RGAFLAHGSL TEPGRSSSLE VTCPGPEAAL ALVGAARRLS IAAKAREVRG
VDRVVVRDGD AIGALLTRLG AHESVLAWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAGARVQRAL EILADEVPEH LAAAGRLRME HKQASLEELG ALADPPLTKD AVAGRIRRLL
AMADKRAQDL GIPGTESNLT EEMADNLAG