WHIA_STRMU
ID WHIA_STRMU Reviewed; 303 AA.
AC Q8DTM9;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=SMU_1304c;
OS Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=210007;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700610 / UA159;
RX PubMed=12397186; DOI=10.1073/pnas.172501299;
RA Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B.,
RA Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S.,
RA Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.;
RT "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; AE014133; AAN58981.1; -; Genomic_DNA.
DR RefSeq; NP_721675.1; NC_004350.2.
DR RefSeq; WP_002263723.1; NC_004350.2.
DR AlphaFoldDB; Q8DTM9; -.
DR SMR; Q8DTM9; -.
DR STRING; 210007.SMU_1304c; -.
DR PRIDE; Q8DTM9; -.
DR EnsemblBacteria; AAN58981; AAN58981; SMU_1304c.
DR KEGG; smu:SMU_1304c; -.
DR PATRIC; fig|210007.7.peg.1169; -.
DR eggNOG; COG1481; Bacteria.
DR HOGENOM; CLU_053282_0_0_9; -.
DR OMA; CDAEAAW; -.
DR PhylomeDB; Q8DTM9; -.
DR Proteomes; UP000002512; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding; Reference proteome.
FT CHAIN 1..303
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376575"
FT DNA_BIND 272..303
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 303 AA; 34191 MW; 44247769B710D465 CRC64;
MSFTTQVKEE ILNLDSADKN ELSAIIKMSG SLGLADKKLS LSIITENAKI ARHIYALLER
LYRINPEIKY HHKTNLRKNR VYTVFLDDNV EQILADLQLS DSFFGIETGI EQQILSDDNA
GRSYLKGAFL STGSIRDPES GKYQLEIFSV YLDHAEDLAK LMQKFMLDTK VIEHKHGAVT
YLQKAEDIMD FLIIIGSMEG MEAFENIKVM RETRNDVNRT SNAETANIAK TINASIKTIN
NINKIKETVG LESLPIELQR IAQIRAAHPD FSIQQIADSL AVPLTKSGVN HRLRKINKIA
EDL