WHIA_STRPS
ID WHIA_STRPS Reviewed; 303 AA.
AC B2IR82;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JUN-2008, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=SPCG_1549;
OS Streptococcus pneumoniae (strain CGSP14).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=516950;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGSP14;
RX PubMed=19361343; DOI=10.1186/1471-2164-10-158;
RA Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.;
RT "Genome evolution driven by host adaptations results in a more virulent and
RT antimicrobial-resistant Streptococcus pneumoniae serotype 14.";
RL BMC Genomics 10:158-158(2009).
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000255|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; CP001033; ACB90801.1; -; Genomic_DNA.
DR RefSeq; WP_000011276.1; NC_010582.1.
DR AlphaFoldDB; B2IR82; -.
DR SMR; B2IR82; -.
DR EnsemblBacteria; ACB90801; ACB90801; SPCG_1549.
DR KEGG; spw:SPCG_1549; -.
DR HOGENOM; CLU_053282_0_0_9; -.
DR OMA; CDAEAAW; -.
DR Proteomes; UP000001682; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; -; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR PANTHER; PTHR37307; PTHR37307; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
DR SUPFAM; SSF55608; SSF55608; 1.
DR TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; DNA-binding.
FT CHAIN 1..303
FT /note="Probable cell division protein WhiA"
FT /id="PRO_0000376579"
FT DNA_BIND 272..303
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ SEQUENCE 303 AA; 34062 MW; AC20DED7D3138041 CRC64;
MSFTVAVKEE ILGQHHLSRH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL ARHLYESFLH
FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA DSFFGLETGI DEAILSDEEA
GRAYLCGAFL ANGSIRDPES GKYQLEISSV YLDHAQGIAS LLQQFLLDAK VLERKKGAVT
YLQRAEDIMD FLIVIGAMQA RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN
NISKIKDIMG LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA
DEL